University of California, Irvine, Colvard Eye Center, Encino, CA, USA.
Cornea. 2010 Feb;29(2):141-5. doi: 10.1097/ICO.0b013e3181b11630.
To evaluate the impact of Hispanic and white ethnicity on the recurrence rates of pterygia after primary excision and conjunctival autograft (CAG) in a southern California population.
A retrospective case-control review comparing 15 Hispanic and 11 white patients with primary nasal pterygia was performed. All participants received pterygium excision with superior limbal CAG by 1 of 3 surgeons and postoperative topical steroids for 2 months. The main outcome measure was recurrence after surgery, defined as fibrovascular tissue over the corneoscleral limbus onto clear cornea in the area of previous pterygium excision.
Average duration of follow-up in the Hispanic and white groups were 9.3 +/- 9.8 months and 13.0 +/- 10.7 months, respectively (P = 0.39). During this follow-up period, there was a statistically significant difference in the pterygium recurrence rate between the Hispanic patients, 6 of 15 (40%), and the white patients, 0 of 11 (0%) (P = 0.02). The average time to recurrence was 3.4 +/- 1.1 months (range, 1.9-5.0). The difference in average age, male/female composition, and follow-up time between the Hispanic and white patient groups studied was not found to be statistically significant (P > 0.05).
Hispanic ethnicity is a potentially important risk factor for recurrence of primary pterygia treated with CAG.
评估在加利福尼亚南部人群中,西班牙裔和白人种族对原发性翼状胬肉切除和结膜自体移植(CAG)后复发率的影响。
对 15 名西班牙裔和 11 名白人原发性鼻侧翼状胬肉患者进行回顾性病例对照研究。所有患者均由 3 位外科医生中的 1 位进行翼状胬肉切除术和上方角膜缘 CAG,并在术后 2 个月内使用局部皮质类固醇。主要观察指标为术后复发,定义为先前翼状胬肉切除区域角膜缘至巩膜处的纤维血管组织覆盖透明角膜。
西班牙裔和白人组的平均随访时间分别为 9.3 ± 9.8 个月和 13.0 ± 10.7 个月(P = 0.39)。在这段随访期间,西班牙裔患者中有 6 例(40%)和白人患者中无 1 例(0%)(P = 0.02)复发,翼状胬肉复发率存在统计学差异。西班牙裔患者的平均复发时间为 3.4 ± 1.1 个月(范围 1.9-5.0)。研究中西班牙裔和白人患者组的平均年龄、男女比例和随访时间差异无统计学意义(P > 0.05)。
西班牙裔种族是 CAG 治疗原发性翼状胬肉后复发的一个重要潜在危险因素。