Fam Anthony, Vohra Reshma, Vadhar Neil R, Dastjerdi Mohammad H
Department of Ophthalmology and Visual Science, Rutgers New Jersey Medical School, Newark, NJ, USA.
J Curr Ophthalmol. 2021 Oct 22;33(3):298-303. doi: 10.4103/joco.joco_99_21. eCollection 2021 Jul-Sep.
To determine the rate and factors affecting pterygium recurrence in the Hispanic population of the Northeastern United States, based on patient demographic information.
In this retrospective cross-sectional study, data were collected on ethnically Hispanic patients from 2013 to 2018 who had primary single-headed pterygia excision and conjunctival autograft, with the minimum of 4-month follow-up time. This study was conducted in an academic institution in the Northeastern United States, with all patients being from the surrounding community.
In 168 Hispanic patients with confirmed primary single-headed pterygium, most pterygia occurred nasally (161/168). The average age of presentation was 46.3 ± 12.0 years (range, 23-77 years). There were 22 recurrences (13.1%), occurring at an average of 3.0 ± 1.6 months (1-8 months). This cohort demonstrated a unimodal recurrence distribution. Age is significantly inversely correlated with the incidence of recurrence ( = -0.219, = 0.004), but not with the size of the recurrent pterygia ( = -0.112, = 0.621). There was no significant difference between recurrence based on gender ( = 0.265), location ( = 0.824), or laterality (right or left eye) ( = 0.213). Mean corrected visual acuity improved from 20/40 to 20/32 after pterygium excision ( < 0.001). Cox regression analysis for age groups shows the risk of recurrence for patients aged 20-29 is 11.4-time that of patients aged 50 and above ( < 0.001).
Recurrence occurred unimodally at around 3 months postoperatively. Younger patients are significantly more susceptible to recurrence. Future studies may seek to determine the incidence of pterygia and their recurrence patterns in relation to occupations and sun exposure time in a geographic area.
基于患者人口统计学信息，确定美国东北部西班牙裔人群中翼状胬肉复发率及影响因素。
在这项回顾性横断面研究中，收集了2013年至2018年患有原发性单头翼状胬肉切除及结膜自体移植且随访时间至少4个月的西班牙裔患者的数据。该研究在美国东北部的一所学术机构进行，所有患者均来自周边社区。
在168例确诊为原发性单头翼状胬肉的西班牙裔患者中，大多数翼状胬肉发生在鼻侧（161/168）。就诊时的平均年龄为46.3±12.0岁（范围23 - 77岁）。有22例复发（13.1%），平均复发时间为3.0±1.6个月（1 - 8个月）。该队列显示复发分布呈单峰型。年龄与复发发生率显著负相关（r = -0.219，P = 0.004），但与复发性翼状胬肉的大小无关（r = -0.112，P = 0.621）。基于性别（P = 0.265）、位置（P = 0.824）或双眼性（右眼或左眼）（P = 0.213）的复发情况无显著差异。翼状胬肉切除术后平均矫正视力从20/40提高到20/32（P < 0.001）。年龄组的Cox回归分析显示，20 - 29岁患者的复发风险是50岁及以上患者的11.4倍（P < 0.001）。
复发在术后约3个月呈单峰型出现。年轻患者复发的易感性显著更高。未来的研究可试图确定某一地理区域内翼状胬肉的发病率及其与职业和日晒时间相关的复发模式。
