Department of OB/GYN and Reproductive Medicine, Faculty of Medicine, University Hospital Arnaud de Villeneuve, INSERM 637, University Montpellier I, 34295 Montpellier cedex 5, France.
Gynecol Endocrinol. 2009 Nov;25(11):717-21. doi: 10.3109/09513590903159599.
This review aims to evaluate whether severe endometriosis has an impact on the outcome of in vitro fertilisation (IVF), whether IVF is associated with specific complications in this context, whether a specific ovarian stimulation protocol is most appropriate, whether the endometrial condition progresses following ovarian stimulation, and whether endometrial cysts pose a specific problem for IVF. In patients with severe endometriosis, IVF represents an effective treatment option for infertility, as a complement to surgery. The prognostic parameters of IVF are identical to those of other patients. However, the risks related to the severity of endometriosis, particularly the risk of ovarian deficiency, need to be considered. Because of this issue, to which endometriosis-related pain often adds, IVF treatment should be initiated as early as possible, using appropriate protocols and after having fully informed the patient about the specific oocytes retrieval-related risks.
本综述旨在评估严重子宫内膜异位症是否会影响体外受精（IVF）的结果，IVF 在这种情况下是否会引起特定的并发症，是否存在最合适的特定卵巢刺激方案，卵巢刺激后子宫内膜状况是否会进展，以及子宫内膜囊肿是否对 IVF 构成特定问题。对于患有严重子宫内膜异位症的患者，IVF 是一种有效的治疗不孕的选择，可作为手术的补充。IVF 的预后参数与其他患者相同。然而，需要考虑与子宫内膜异位症严重程度相关的风险，特别是卵巢功能不全的风险。由于这个问题，以及子宫内膜异位症相关疼痛经常带来的影响，应尽早使用适当的方案并充分告知患者与特定卵母细胞采集相关的风险，开始 IVF 治疗。
