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10%氢氧化钠化学削甲术治疗糖尿病患者嵌甲

Chemical matricectomy with 10% sodium hydroxide for the treatment of ingrown toenails in people with diabetes.

机构信息

Department of Dermatology, Ministry of Health, Diskapi Yildirim Beyazit Education and Research Hospital, Ankara, Turkey.

出版信息

Dermatol Surg. 2010 Feb;36(2):219-22. doi: 10.1111/j.1524-4725.2009.01351.x. Epub 2009 Nov 10.

Abstract

BACKGROUND

Treatment of ingrown toenails using chemical matricectomy in patients with diabetes has been difficult, because delayed wound healing, wound infections, and digital ischemia can interfere with the procedure. Chemical matricectomy with 10% sodium hydroxide is an effective treatment for ingrown toenails in a normal population.

OBJECTIVES

Investigation of the effectiveness and safety of chemical matricectomy with 10% sodium hydroxide solution for ingrown toenails in patients with diabetes.

MATERIAL AND METHODS

Thirty patients with diabetes with 40 ingrown toenails and 30 patients without diabetes with 41 ingrown toenails were enrolled in the study. After partial avulsion of the affected edge, germinal matrix was treated for 1 minute with 10% sodium hydroxide. Patients were observed on alternate days until complete healing was achieved and followed for up to 24 months for recurrence.

RESULTS

Assessment of the treatment in both groups for complete healing, postoperative pain, tissue damage, drainage, infections, and rate of recurrences revealed no statistically significant difference.

CONCLUSIONS

The partial avulsion of the affected edge and the treatment of the germinal matrix for 1 minute with 10% sodium hydroxide preceded by matrix curettage is an effective and safe treatment modality for ingrown toenails in people with diabetes.

摘要

背景

糖尿病患者行化学拔甲术治疗嵌甲较为困难,因为延迟愈合、伤口感染和指端缺血会干扰手术过程。10%氢氧化钠化学拔甲术是一种治疗正常人群嵌甲的有效方法。

目的

探讨 10%氢氧化钠溶液治疗糖尿病患者嵌甲的有效性和安全性。

材料和方法

本研究纳入了 30 例糖尿病伴 40 个嵌甲和 30 例无糖尿病伴 41 个嵌甲的患者。在部分切除受累边缘后,用 10%氢氧化钠溶液处理生发基质 1 分钟。患者隔天观察,直至完全愈合,并随访 24 个月,观察复发情况。

结果

两组完全愈合、术后疼痛、组织损伤、引流、感染和复发率的评估均无统计学差异。

结论

受累边缘的部分切除和 10%氢氧化钠溶液处理 1 分钟,随后行甲床刮除术,是治疗糖尿病患者嵌甲的一种有效且安全的方法。

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