Kocyigit Pelin, Bostanci Seher, Ozdemir Esin, Gürgey Erbak
Department of Dermatology, Ankara University Medical School, 06100 Ankara, Turkey.
Dermatol Surg. 2005 Jul;31(7 Pt 1):744-7; discussion 747. doi: 10.1097/00042728-200507000-00002.
Sodium hydroxide matricectomy is a successful method for the treatment of ingrown toenails. This study was designed to evaluate the optimal sodium hydroxide application period providing high success rates with minimal postoperative morbidity.
Sixty-six patients with 225 ingrown nail edges were treated in three groups receiving 30-second, 1-minute, and 2-minute applications of sodium hydroxide. Each patient was reviewed postoperatively for pain, drainage, and tissue damage. The median long-term follow-up period was 14 months.
The success rate of the therapy was 70.9% in the first group, 92.7% in the second group, and 94.4% in the third group. In all groups, about half of the patients experienced minimal pain within 48 hours following the operation, but only in the third group, 20% of the patients had minimal pain, which continued about 1 week. Drainage and tissue damage were minimal or mild in all groups and disappeared within 3 weeks in the first and second groups but were prolonged to 6 weeks in the third group.
The success rate of 30-second application is significantly lower than 1-minute and 2-minute applications. Although the success rates of the latter two procedures are similar, the prolonged healing time is the disadvantage of the 2-minute application. We conclude that 1-minute application of 10% sodium hydroxide is simple, safe, and highly effective for the treatment of ingrown nails.
氢氧化钠基质切除术是治疗嵌甲的一种成功方法。本研究旨在评估能提供高成功率且术后发病率最低的最佳氢氧化钠应用时间。
66例患有225个嵌甲边缘的患者被分为三组，分别接受30秒、1分钟和2分钟的氢氧化钠应用治疗。对每位患者术后的疼痛、引流情况及组织损伤进行评估。中位长期随访期为14个月。
第一组治疗成功率为70.9%，第二组为92.7%，第三组为94.4%。所有组中，约一半患者在术后48小时内经历轻微疼痛，但仅在第三组中，20%的患者有轻微疼痛，持续约1周。所有组的引流及组织损伤均轻微或不严重，第一组和第二组在3周内消失，而第三组则延长至6周。
30秒应用的成功率显著低于1分钟和2分钟应用。尽管后两种方法的成功率相似，但2分钟应用的缺点是愈合时间延长。我们得出结论，10%氢氧化钠1分钟应用治疗嵌甲简单、安全且高效。
