Institute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University, Room 719, No. 17, Xu-Zhou Road, Taipei 10055, Taiwan.
Am J Public Health. 2010 Jan;100(1):165-70. doi: 10.2105/AJPH.2008.159004.
We estimated loss of quality-adjusted life expectancy (QALE) among motorcyclists in Taiwan who sustained head injuries while wearing or not wearing a helmet.
Patients with head injuries (n=3328) were grouped into categories representing good and poor outcomes (moderate disability or death) at discharge. After linkage with the National Mortality Registry, survival functions were determined and extrapolated over a 50-year period on the basis of the survival ratio between patients and age- and gender-matched reference populations, as calculated from available Taiwan vital statistics. Survival functions were then multiplied by scores from quality-of-life measures.
Percentages of good and poor outcomes were 87.2% and 12.8%, respectively, in the helmeted group and 66.4% and 33.6% in the nonhelmeted group. The mean QALE for helmeted motorcyclists, calculated by weighting percentages of good and poor outcomes, was 31.7 quality-adjusted life-years (QALYs), with an average loss of 5.8 QALYs. For nonhelmeted motorcyclists, the mean QALE was 25.9 QALYs, with a loss of 10.7 QALYs.
Helmet use could save approximately 5 QALYs among motorcyclists sustaining head injuries. Future cost-effectiveness analysis can calculate the incremental cost-effectiveness ratio for regulation of helmet use.
本研究旨在评估台湾地区因骑乘摩托车导致头部受伤的患者在佩戴和未佩戴头盔时,生活质量调整预期寿命(QALE)的损失情况。
本研究将因头部受伤而住院的患者(n=3328)分为预后良好(中度残疾或存活)和预后不良(死亡)两组。通过与国家死亡登记系统进行链接,确定了两组患者的生存函数,并根据患者与年龄和性别相匹配的参考人群的生存比率,对 50 年内的生存情况进行了外推,该生存比率是根据可获得的台湾生命统计数据计算得出的。然后,将生存函数与生活质量测量得分相乘。
在佩戴头盔的患者中,预后良好和预后不良的比例分别为 87.2%和 12.8%,而在未佩戴头盔的患者中,这两个比例分别为 66.4%和 33.6%。通过对预后良好和预后不良的比例进行加权计算,佩戴头盔的摩托车骑手的平均 QALE 为 31.7 个质量调整生命年(QALY),平均损失 5.8 个 QALY。对于未佩戴头盔的摩托车骑手,平均 QALE 为 25.9 个 QALY,平均损失 10.7 个 QALY。
头盔的使用可以使因头部受伤而骑乘摩托车的患者平均多获得约 5 个 QALY。未来的成本效益分析可以计算头盔使用监管的增量成本效益比。