Northumberland, Tyne and Wear NHS Trust-PACE Office, St Georges Park, Morpeth, Northumberland, UK.
Acta Psychiatr Scand. 2010 Apr;121(4):315-9. doi: 10.1111/j.1600-0447.2009.01505.x. Epub 2009 Nov 12.
To investigate the incidence and range of diagnostic groups in patients with first-episode psychosis (FEP) in a defined geographical area.
An observational database was set up on all patients aged 16 years and over presenting with FEP living in a county in Northern England between 1998 and 2005.
The incidence of all FEP was 30.95/100,000. The largest diagnostic groups were psychotic depression (19%) and acute and transient psychotic disorder (19%). Fifty-four per cent of patients were aged 36 years and over. Patients with schizophrenia spectrum disorder only accounted for 55% of cases.
This clinical database revealed marked diversity in age and diagnostic groups in FEP with implications for services and guidelines. These common presentations of psychoses are grossly under researched, and no treatment guidelines currently exist for them.
调查特定地理区域内首发精神病（FEP）患者的诊断组别发生率和范围。
在英格兰北部的一个县，对所有于 1998 年至 2005 年间出现 FEP 的 16 岁及以上的患者，建立了一个观察性数据库。
所有 FEP 的发病率为 30.95/100,000。最大的诊断组别为精神病性抑郁症（19%）和急性和短暂性精神病障碍（19%）。54%的患者年龄在 36 岁及以上。精神分裂症谱系障碍患者仅占 55%。
该临床数据库显示，FEP 的年龄和诊断组别存在明显差异，这对服务和指南有影响。这些常见的精神病表现研究不足，目前尚无针对它们的治疗指南。
