Department of Oral and Maxillofacial Surgery, Alexandroupolis University General Hospital, Alexandroupolis, Greece.
Dermatol Surg. 2010;36(1):15-22. doi: 10.1111/j.1524-4725.2009.01379.x. Epub 2009 Nov 13.
Nonmelanoma skin cancer (NMSC) constitutes the most common malignancy in Caucasians. Epidemiological data derive, mainly, from studies in the United States, Australia, and Northern Europe, whereas data from Mediterranean Europe are scarce.
To provide information on the epidemiology of surgically treated NMSC of the head and neck in the region of Thrace, Northern Greece, and to evaluate the surgical treatment given.
A retrospective review of patients surgically treated from 2004 to 2006 was conducted. Data on demographics, histology and skin cancer characteristics, and treatment efficacy and recurrence rate were extracted and analyzed.
One hundred seventy-nine NMSCs of the head and neck were excised and histopathologically confirmed in 160 patients, with the majority (58.7%) classified as Fitzpatrick skin type III. Histology included 125 basal cell carcinomas (BCCs) and 54 squamous cell carcinomas (SCCs). The mean age was 70.6 +/- 10.1 (range 38-97). Tumor size ranged between 2 and 50 mm. Excision with 5-mm margins was performed in every case, and the defects were closed mainly using local flaps. Incomplete excision was limited to 3.9% of cases, and the recurrence rate was 1.7%. The study revealed similar characteristics between BCC and SCC regarding age and sex but significant differences in terms of location and size.
Surgical resection achieves a satisfactory NMSC clearance rate in the head and neck.
非黑色素瘤皮肤癌（NMSC）是白种人中最常见的恶性肿瘤。流行病学数据主要来源于美国、澳大利亚和北欧的研究，而来自地中海欧洲的数据则很少。
提供希腊北部色雷斯地区头颈部手术治疗的 NMSC 流行病学信息，并评估所采用的手术治疗方法。
对 2004 年至 2006 年期间接受手术治疗的患者进行回顾性研究。提取并分析了患者的人口统计学、组织病理学和皮肤癌特征、治疗效果和复发率等数据。
在 160 名患者中，共切除并经组织病理学证实了 179 例头颈部 NMSC，其中大多数（58.7%）为 Fitzpatrick 皮肤类型 III。组织学包括 125 例基底细胞癌（BCC）和 54 例鳞状细胞癌（SCC）。平均年龄为 70.6 +/- 10.1 岁（范围为 38-97 岁）。肿瘤大小在 2 至 50 毫米之间。所有病例均采用 5 毫米边缘切除，主要使用局部皮瓣闭合缺损。不完全切除限于 3.9%的病例，复发率为 1.7%。研究表明，BCC 和 SCC 在年龄和性别方面具有相似的特征，但在位置和大小方面存在显著差异。
手术切除对头颈部 NMSC 具有令人满意的清除率。
