自发形成的单层囊泡。
Spontaneously formed unilamellar vesicles.
作者信息
Nieh Mu-Ping, Kucerka Norbert, Katsaras John
机构信息
Canadian Neutron Beam Centre, Steacie Institute for Molecular Sciences, Chalk River Laboratories, National Research Council Canada, Chalk River, Ontario, Canada.
出版信息
Methods Enzymol. 2009;465:3-20. doi: 10.1016/S0076-6879(09)65001-1.
Mixtures of long- and short-chain phospholipids can spontaneously form uniform unilamellar vesicles (ULVs) with diameters 50 nm (polydispersities of <0.3) or less. The morphology of these ULVs has mainly been characterized using small angle neutron scattering (SANS), a technique highly suited for the study of hydrogenous materials. Once formed, these ULVs have turned out to be highly stable and show great promise as imaging and therapeutic carriers.
长链和短链磷脂的混合物可以自发形成直径50纳米（多分散性小于0.3）或更小的均匀单层囊泡（ULV）。这些ULV的形态主要通过小角中子散射（SANS）来表征，这是一种非常适合研究含氢材料的技术。一旦形成，这些ULV已被证明具有高度稳定性，并作为成像和治疗载体显示出巨大潜力。
Zotero 插件