Department of Physical Medicine and Rehabilitation, School of Medicine, University of Roma La Sapienza, p.le A. Moro 5, 00185 Roma, Italy.
J Clin Epidemiol. 2010 May;63(5):550-7. doi: 10.1016/j.jclinepi.2009.08.001. Epub 2009 Nov 12.
To determine the measurement properties of an Italian Version of the Lower Extremity Functional Scale (LEFS) in patients with lower extremity musculoskeletal dysfunction.
This is a prospective methodological study of repeated measures with a sample of 250 consecutive patients. Reliability, validity, and responsiveness were evaluated.
The Italian version of the LEFS showed a high degree of internal consistency with a Cronbach alpha of 0.94 (95% confidence interval [CI]: 0.91, 0.96). The test-retest reliability was high for both intra-interviewer and inter-interviewer measures with an ICC((2,1 and 2,k)) of 0.91 (95% CI: 0.86, 0.93) and 0.89 (95% CI: 0.83, 0.91), respectively. The LEFS showed a better correlation with the 36-Item Short-Form Health Survey (SF-36) physical component summary score rather than with the SF-36 mental component summary score both at the initial assessment (r=0.61 and 0.26, respectively) and at the discharge (r=0.72 and 0.22, respectively). Receiver operating characteristic curve analysis revealed a large responsiveness for the LEFS (area under the curve [AUC]=0.97) and a moderate responsiveness for the SF-36 (AUC=0.68).
The Italian version of the LEFS is a valid, reliable, and responsive tool that can be used to measure function in Italian patients with lower extremity musculoskeletal dysfunction.
确定下肢功能量表（LEFS）意大利版本在下肢肌肉骨骼功能障碍患者中的测量特性。
这是一项具有 250 例连续患者样本的前瞻性重复测量方法学研究。评估了可靠性、有效性和反应性。
LEFS 的意大利版本显示出高度的内部一致性，Cronbach α 为 0.94（95%置信区间[CI]：0.91，0.96）。无论是内部测试者之间还是内部测试者与外部测试者之间的测试-再测试可靠性都很高，ICC（2,1 和 2,k）分别为 0.91（95% CI：0.86，0.93）和 0.89（95% CI：0.83，0.91）。LEFS 与 36 项简短健康调查问卷（SF-36）身体成分综合评分的相关性优于与 SF-36 心理成分综合评分的相关性，无论是在初始评估（r=0.61 和 0.26）还是在出院时（r=0.72 和 0.22）。受试者工作特征曲线分析显示，LEFS 具有较大的反应性（曲线下面积[AUC]=0.97），SF-36 具有中等的反应性（AUC=0.68）。
LEFS 的意大利版本是一种有效、可靠且反应灵敏的工具，可用于评估意大利下肢肌肉骨骼功能障碍患者的功能。
