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患有图雷特综合征的名人?

Famous people with Gilles de la Tourette syndrome?

机构信息

Department of Neurology, Amedeo Avogadro University, Novara, Italy.

出版信息

J Psychosom Res. 2009 Dec;67(6):485-90. doi: 10.1016/j.jpsychores.2009.07.003. Epub 2009 Sep 30.

Abstract

Virtually no neurologist nor psychiatrist today can be unaware of the diagnosis of Gilles de la Tourette syndrome (GTS). Although the eponymous description by Dr. Georges Gilles de la Tourette was published in 1885, familiarity with this syndrome has been achieved only recently. In this article, the two most renown accounts of exceptional individuals retrospectively diagnosed with GTS are critically analyzed: British lexicographer Samuel Johnson and Austrian musician Wolfgang Amadeus Mozart. In both cases, clinical descriptions have been retrieved from written documents predating Gilles de la Tourette's original publication. The case for Samuel Johnson having GTS is strong, mainly based on Boswell's extensive biographical account. Johnson was reported to have a great range of tics and compulsions, including involuntary utterances, repetitive ejaculations, and echo-phenomena. On the other hand, there is circumstantial evidence that Mozart may have had hyperactivity, restlessness, sudden impulses, odd motor behaviors, echo/palilalia, love of nonsense words, and scatology, the latter being documented in autograph letters ("coprographia"). However, the evidence supporting the core features of GTS, i.e., motor and vocal tics, is rather inconsistent. Thus, GTS seems to be an implausible diagnosis in Mozart's medical history and completely unrelated to his undisputed musical genius.

摘要

今天,几乎没有神经学家或精神科医生不知道 Gilles de la Tourette 综合征 (GTS) 的诊断。尽管以医生 Georges Gilles de la Tourette 的名字命名的描述发表于 1885 年,但直到最近才对这种综合征有所了解。在本文中,批判性地分析了 retrospectively diagnosed with GTS 的两位最著名的特殊个体的案例:英国词典编纂家塞缪尔·约翰逊和奥地利音乐家沃尔夫冈·阿玛多伊斯·莫扎特。在这两种情况下,临床描述都来自于 Gilles de la Tourette 原始出版物之前的书面文件。塞缪尔·约翰逊患有 GTS 的可能性很大,主要基于 Boswell 的广泛传记描述。据报道,约翰逊有很多抽搐和强迫症,包括不由自主的言语、重复射精和回声现象。另一方面,有间接证据表明莫扎特可能患有多动、不安、冲动、奇怪的运动行为、回声/重复言语、喜欢无意义的词以及淫秽言语,后者在亲笔信(“coprographia”)中有记录。然而,支持 GTS 核心特征(即运动和声音抽搐)的证据并不一致。因此,GTS 似乎不太可能是莫扎特病史中的诊断,与他无可争议的音乐天才完全无关。

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