London Health Sciences Center, Victoria Campus, London, Ontario, Canada.
J Crit Care. 2010 Sep;25(3):406-12. doi: 10.1016/j.jcrc.2009.10.001. Epub 2009 Nov 14.
The study was undertaken to evaluate the quality of life of survivors of septic illness.
A questionnaire survey of survivors of septic illness (experimental group) and acute myocardial infarction (control group) was conducted using information from the Adult Neuropsychological History and the Sickness Impact Profile forms. Eight patients diagnosed with sepsis (using the Bone et al 1992 criteria [Bone RC, Sprung CL, Sibbald WJ. Crit Care Med 1992;20:724-726]) and 15 patients diagnosed with acute myocardial infarction participated in the study.
On the Sickness Impact Profile, greater difficulty with work was reported in the sepsis group than in the cardiac control group (P < .04). When retired individuals were excluded from the analysis, individuals in the sepsis group reported more symptoms on the sensory, physical, and behavior sections of the Adult Neuropsychological History form and greater difficulty with sleep and rest, emotional behavior, body care and movement, and physical and psychosocial functioning on the Sickness Impact Profile. As well, more individuals in the sepsis than the control group endorsed symptoms related to problem solving, concentration, memory, sensory, and physical ability.
Individuals surviving sepsis may have problems with physical, sensory, emotional, and cognitive functioning that become most apparent when involved in more challenging activities, such as working.
本研究旨在评估脓毒症幸存者的生活质量。
采用成人神经心理病史和疾病影响量表形式，对脓毒症（实验组）和急性心肌梗死（对照组）幸存者进行问卷调查。本研究纳入了 8 例符合脓毒症诊断标准（使用 Bone 等 1992 年标准[Bone RC，Sprung CL，Sibbald WJ。Crit Care Med 1992；20：724-726]）和 15 例急性心肌梗死患者。
在疾病影响量表上，脓毒症组报告的工作困难比心脏对照组更严重（P<0.04）。排除退休人员后，脓毒症组在成人神经心理病史表的感觉、身体和行为部分以及睡眠和休息、情绪行为、身体护理和运动以及身体和心理社会功能方面报告了更多症状，且脓毒症组在疾病影响量表上报告的工作困难更严重。此外，脓毒症组比对照组有更多的人报告与解决问题、注意力、记忆、感觉和身体能力相关的症状。
脓毒症幸存者可能存在身体、感觉、情绪和认知功能方面的问题，当他们参与更具挑战性的活动（如工作）时，这些问题会变得更加明显。
