Department of Paediatric Neurology and Developmental Medicine, Dr. von Hauner's Children's Hospital, University of Munich, Lindwurmstr. 4, 80337 Munich, Germany.
Eur J Paediatr Neurol. 2010 Jan;14(1):45-66. doi: 10.1016/j.ejpn.2009.09.005. Epub 2009 Nov 14.
An interdisciplinary European group of clinical experts in the field of movement disorders and experienced Botulinum toxin users has updated the consensus for the use of Botulinum toxin in the treatment of children with cerebral palsy (CP). A problem-orientated approach was used focussing on both published and practice-based evidence. In part I of the consensus the authors have tabulated the supporting evidence to produce a concise but comprehensive information base, pooling data and experience from 36 institutions in 9 European countries which involves more than 10,000 patients and over 45,000 treatment sessions during a period of more than 280 treatment years. In part II of the consensus the Gross Motor Function Measure (GMFM) and Gross Motor Function Classification System (GMFCS) based Motor Development Curves have been expanded to provide a graphical framework on how to treat the motor disorders in children with CP. This graph is named "CP(Graph) Treatment Modalities - Gross Motor Function" and is intended to facilitate communication between parents, therapists and medical doctors concerning (1) achievable motor function, (2) realistic goal-setting and (3) treatment perspectives for children with CP. The updated European consensus 2009 summarises the current understanding regarding an integrated, multidisciplinary treatment approach using Botulinum toxin for the treatment of children with CP.
一个跨学科的欧洲运动障碍领域的临床专家小组和有经验的肉毒毒素使用者更新了肉毒毒素治疗脑瘫儿童的共识。采用以问题为导向的方法,重点关注已发表的和基于实践的证据。在共识的第一部分,作者列出了支持证据,以形成一个简洁但全面的信息基础,汇集了来自 9 个欧洲国家的 36 个机构的数据和经验,涉及 10000 多名患者和超过 45000 次治疗,时间跨度超过 280 年。在共识的第二部分,粗大运动功能测量(GMFM)和粗大运动功能分类系统(GMFCS)的运动发育曲线已经扩展,为如何治疗脑瘫儿童的运动障碍提供了一个图形框架。这个图形被命名为“CP(Graph)治疗模式-粗大运动功能”,旨在促进家长、治疗师和医生之间的沟通,涉及(1)可实现的运动功能,(2)现实的目标设定,以及(3)脑瘫儿童的治疗前景。2009 年的更新的欧洲共识总结了目前关于使用肉毒毒素治疗脑瘫儿童的综合、多学科治疗方法的理解。