Ernst Daniel, Sanhueza A Luis, Rojas Luis, Aizman Andrés
Departamento de Medicina Interna, Pontificia Universidad Católica de Chile, Santiago de Chile.
Rev Med Chil. 2009 Aug;137(8):1051-3. Epub 2009 Nov 4.
Fever of unknown origin (FUO) can be caused by tumors, especially those arising from the hematopoietic system. Multiple myeloma can also cause fever but it is not a common cause of fever of unknown origin. We report a 53 year-old man presenting with fever lasting eight weeks. An extensive study for common causes of FUO was negative. The appearance of hypercalcemia and proteinuria during the evolution suggested the presence of a multiple myeloma, that was confirmed with a bone marrow biopsy. Thalidomide and dexametasone were prescribed with resolution of fever.
不明原因发热（FUO）可由肿瘤引起，尤其是造血系统来源的肿瘤。多发性骨髓瘤也可引起发热，但它并非不明原因发热的常见病因。我们报告一名53岁男性，发热持续8周。针对不明原因发热的常见病因进行的广泛检查均为阴性。病程中出现高钙血症和蛋白尿提示存在多发性骨髓瘤，骨髓活检证实了这一点。给予沙利度胺和地塞米松治疗后发热消退。
