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腹横肌平面阻滞,当作为包括鞘内吗啡的多模式治疗方案的一部分时,并不能改善剖宫产术后的镇痛效果。

The transversus abdominis plane block, when used as part of a multimodal regimen inclusive of intrathecal morphine, does not improve analgesia after cesarean delivery.

机构信息

Department of Anesthesia and Pain Management, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.

出版信息

Reg Anesth Pain Med. 2009 Nov-Dec;34(6):586-9. doi: 10.1097/aap.0b013e3181b4c922.

Abstract

BACKGROUND AND OBJECTIVES

The transversus abdominis plane (TAP) block has been shown to provide analgesia for lower abdominal wall incisions. We evaluated the efficacy of the TAP block for post-cesarean delivery (CD) patients used as a part of a multimodal regimen.

METHODS

Women undergoing elective CD under spinal anesthesia were randomized to receive the TAP block with ropivacaine (n = 50) or placebo (n = 50), in addition to a standard postoperative analgesic regimen inclusive of intrathecal opioids. At the end of the surgical procedure, all the patients received bilateral TAP blocks under real-time ultrasound guidance, with either 20 mL of ropivacaine 0.375% or saline, on each side. Each patient was assessed at 6, 12, 24, and 48 hrs postoperatively, and again 6 weeks after the surgical procedure. The primary outcome was the difference in visual analog scale pain scores with movement at 24 hrs postpartum. Other outcomes assessed were analgesic consumption, maternal satisfaction, and incidence of adverse effects.

RESULTS

One hundred women were recruited, and 96 completed the study. The mean (SD) visual analog scale pain scores on movement at 24 hrs were not different between the ropivacaine and placebo groups (3.4 [2.4] and 3.2 [2.2] cm, respectively, P = 0.47). The pain scores at other times, and the supplemental opioid consumption, were also similar between the 2 groups. The overall incidence of pain at 6 weeks postpartum was 8.3%.

CONCLUSIONS

The TAP block, when used as part of a multimodal regimen inclusive of intrathecal morphine, does not improve the quality of post-CD analgesia.

摘要

背景与目的

腹横肌平面(TAP)阻滞已被证明可提供下腹部壁切口的镇痛。我们评估了 TAP 阻滞在作为多模式方案一部分的剖宫产(CD)后患者中的疗效。

方法

在脊髓麻醉下接受择期 CD 的女性随机分为接受罗哌卡因 TAP 阻滞(n = 50)或安慰剂(n = 50)组,此外还接受包括鞘内阿片类药物在内的标准术后镇痛方案。在手术结束时,所有患者均在实时超声引导下接受双侧 TAP 阻滞,每侧给予 20 mL 0.375%罗哌卡因或生理盐水。每位患者在术后 6、12、24 和 48 小时以及手术 6 周后进行评估。主要结局是产后 24 小时运动时视觉模拟评分疼痛评分的差异。评估的其他结局包括镇痛药物消耗、产妇满意度和不良反应发生率。

结果

共招募了 100 名女性,其中 96 名完成了研究。罗哌卡因和安慰剂组在 24 小时运动时的平均(SD)视觉模拟评分疼痛评分无差异(分别为 3.4 [2.4]和 3.2 [2.2] cm,P = 0.47)。其他时间的疼痛评分和补充阿片类药物消耗也相似。产后 6 周时整体疼痛发生率为 8.3%。

结论

TAP 阻滞,当作为包括鞘内吗啡在内的多模式方案的一部分时,不能改善 CD 后镇痛质量。

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