He Feng, Yang Jun, Zhang Qing-Ping, Cui Xi-Yun
College of Life Science, Shandong Normal University, Jinan 250014, China.
Zhen Ci Yan Jiu. 2009 Aug;34(4):279-82.
Clinical practice has demonstrated that acupuncture of Jing (Well)-points is effective in the treatment of cerebral infarction, vascular dementia and other problems induced by acute or chronic cerebral ischemia. In recent years, abundant results from animal experiments of cerebral ischemic (CI) injury have preliminarily uncovered some underlying mechanisms of acupuncture of Jing points in reducing CI injury, including 1) scavenging active free radicals, 2) decreasing calcium overloading, 3) regulating inflammation-related cytokines expression, and 4) upregulating the expression of anti-apoptosis genes. However, further studies are needed because of the complexity of the development of ischemic cerebral injury.
临床实践表明，针刺井穴治疗脑梗死、血管性痴呆等急慢性脑缺血所致病症有效。近年来，大量脑缺血（CI）损伤动物实验结果初步揭示了针刺井穴减轻CI损伤的一些潜在机制，包括：1）清除活性自由基；2）减轻钙超载；3）调节炎症相关细胞因子表达；4）上调抗凋亡基因表达。然而，由于缺血性脑损伤发展过程的复杂性，仍需进一步研究。
