Chopra P, Narula J P
Department of Pathology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi.
Int J Cardiol. 1991 Jan;30(1):109-12. doi: 10.1016/0167-5273(91)90131-8.
We have studied four cases of acute rheumatic carditis at autopsy in which the cardiac valves revealed rheumatic vegetations. The features of these vegetations were investigated by scanning electron microscopy. There was a loss of the normal mosaic arrangement of endothelial cells and marked architectural modifications of the valvar collagen. These features explain well the pathologic processes of rheumatic valvitis and the infective complications, if any, thereof. To the best of our knowledge, this is the first time that an analysis has been made of the structure of the surface of rheumatic vegetations.
我们对4例急性风湿性心内膜炎尸检病例进行了研究，这些病例的心脏瓣膜可见风湿性赘生物。通过扫描电子显微镜对这些赘生物的特征进行了研究。发现内皮细胞正常的镶嵌排列消失，瓣膜胶原的结构有明显改变。这些特征很好地解释了风湿性心内膜炎的病理过程及其可能出现的感染性并发症。据我们所知，这是首次对风湿性赘生物表面结构进行分析。
