Department of Preclinical Sciences, The University of the West Indies, Trinidad.
Arch Physiol Biochem. 2010 Feb;116(1):21-7. doi: 10.3109/13813450903397638.
To determine whether elevated levels of troponin T are associated with altered lipid profile.
Data were collected from 205 patients each of whom presented elevated troponin T levels.
195 patients presented with suspected myocardial infarction, 10 patients did not. Of which 68 had medium, 107 high and 20 presented with very high troponin T levels. The proportions were significantly different (p = 0.000215). Regression analysis showed that troponin T level was a useful quadratic predictor of total cholesterol (p = 0.000), triglycerides (p = 0.003), and low density cholesterol (p = 0.000); and a useful linear predictor of TC/HC ratio (p = 0.001).
The occurrence of myocardial infarction is associated with elevated troponin T levels; troponin T is positively correlated with total cholesterol, triglycerides, LDL and TC/HC ratio and negatively correlated with HDL. TC/HC ratio was not found to be a useful predictor of the likelihood of MI.
确定肌钙蛋白 T 水平升高是否与血脂谱改变有关。
从 205 名肌钙蛋白 T 水平升高的患者中收集数据。
195 例患者疑似心肌梗死，10 例患者不疑。其中 68 例为中等，107 例为高，20 例为非常高的肌钙蛋白 T 水平。比例有显著差异（p = 0.000215）。回归分析显示，肌钙蛋白 T 水平是总胆固醇（p = 0.000）、甘油三酯（p = 0.003）和低密度胆固醇（p = 0.000）的有用二次预测因子；是 TC/HC 比值（p = 0.001）的有用线性预测因子。
心肌梗死的发生与肌钙蛋白 T 水平升高有关；肌钙蛋白 T 与总胆固醇、甘油三酯、LDL 和 TC/HC 比值呈正相关，与 HDL 呈负相关。TC/HC 比值不能作为 MI 发生可能性的有用预测因子。
