Fushiki Hiroaki, Junicho Makiko, Kanazawa Yuuji, Aso Shin, Watanabe Yukio
Department of Otolaryngology, Head & Neck Surgery, University of Toyama, Toyama, Japan.
Acta Otolaryngol. 2010 May;130(5):559-64. doi: 10.3109/00016480903311245.
In clinical practice, sudden low-tone loss other than acute low-tone sensorineural hearing loss (ALHL) shows a potential for recurrence.
ALHL is often associated with recurrence and/or progression to Ménière's disease. We examined the prognosis of patients with sudden low-tone loss who were not classified in the audiometric definition of ALHL.
Sixty-three patients diagnosed at the university hospital with idiopathic sudden low-tone loss of sensorineural hearing loss and without subjective vertigo were followed up in the long term with a mean of over 4 years. The rates of recurrence and/or progression to Ménière's disease for patients with low-tone loss type other than ALHL (non-ALHL) were compared with those for ALHL patients.
The recovery rate at the initial treatment was 47.6% for non-ALHL and 62.9% for ALHL. A Kaplan-Meier plot indicated that cumulative recurrence rates for non-ALHL were 20.2% at 1 year and 43.5% at 5 years, whereas the rates for ALHL were 12.2% at 1 year and 31.3% at 5 years. There was no statistically significant difference between the two patient groups.
在临床实践中，除急性低频感音神经性听力损失（ALHL）外的突发性低频听力损失有复发的可能性。
ALHL常与复发和/或进展为梅尼埃病相关。我们研究了未被纳入ALHL听力测定定义的突发性低频听力损失患者的预后情况。
63例在大学医院被诊断为特发性突发性低频感音神经性听力损失且无主观眩晕的患者接受了平均超过4年的长期随访。将非ALHL型低频听力损失患者（非ALHL）与ALHL患者的复发和/或进展为梅尼埃病的发生率进行比较。
非ALHL患者初始治疗时的恢复率为47.6%，ALHL患者为62.9%。Kaplan-Meier曲线表明，非ALHL患者1年时的累积复发率为20.2%，5年时为43.5%，而ALHL患者1年时的复发率为12.2%，5年时为31.3%。两组患者之间无统计学显著差异。
