血清血栓素 B2 水平与卵巢子宫内膜异位症患者的盆腔痛不相关。
Thrombospondin-1 serum levels do not correlate with pelvic pain in patients with ovarian endometriosis.
机构信息
Department of Obstetrics and Gynecology, Clínica Universitaria de Navarra, University of Navarra, Pamplona, Spain.
出版信息
J Ovarian Res. 2009 Nov 16;2(1):18. doi: 10.1186/1757-2215-2-18.
OBJECTIVE
Thrombospondin-1 serum levels is correlate with pelvic pain in patients with ovarian endometriosis.
PATIENTS
Thrombospondin-1 serum levels were prospectively analysed in 51 patients (group A asymptomatic patients or patients presenting mild dysmenorrhea and women comprised group B severe dysmenorrhea and/or chronic pelvic pain and/or dyspareunia) who underwent surgery for cystic ovarian endometriosis to asses whether a correlation exists among thrombospondin-1 serum levels and pelvic pain.
RESULTS
From 56 patients, five cases were ultimately excluded, because the histological diagnosis was other than cystic ovarian endometriosis (2 teratomas and 3 haemorrhagic cysts). The mean thrombospondin-1 serum levels in group A was 256,69 pg/ml_+37,07 and in group B was 291,41 pg/ml + 35,59.
CONCLUSION
Pain symptoms in ovarian endometriosis is not correlated with thrombospondin-1 serum levels.
目的
血清中凝血酶敏感蛋白-1 水平与卵巢子宫内膜异位症患者盆腔痛相关。
患者
前瞻性分析了 51 例（A 组无症状或仅表现为轻度痛经的患者；B 组为重度痛经和/或慢性盆腔痛和/或性交痛的患者）因囊性卵巢子宫内膜异位症行手术治疗的患者的血清中凝血酶敏感蛋白-1 水平，以评估凝血酶敏感蛋白-1 血清水平与盆腔痛之间是否存在相关性。
结果
56 例患者中，最终有 5 例被排除，因为组织学诊断并非囊性卵巢子宫内膜异位症（2 例为畸胎瘤，3 例为出血性囊肿）。A 组的平均凝血酶敏感蛋白-1 血清水平为 256.69pg/ml+37.07，B 组为 291.41pg/ml+35.59。
结论
卵巢子宫内膜异位症的疼痛症状与凝血酶敏感蛋白-1 血清水平无关。
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