Burnham Institute for Medical Research, La Jolla, CA 92037, USA.
Mol Cell. 2009 Nov 13;36(3):353-4. doi: 10.1016/j.molcel.2009.10.023.
In this issue of Molecular Cell, Kim et al. (2009) describe the steps involved in the direct activation of the proapoptotic proteins BAX and BAK by their BH3-only partners, resolving the controversy regarding direct versus indirect activation of these proteins.
在本期《分子细胞》中,Kim 等人(2009)描述了其 BH3 仅蛋白伴侣直接激活促凋亡蛋白 BAX 和 BAK 所涉及的步骤,解决了关于这些蛋白直接激活还是间接激活的争议。