Taner B, Willingham D L, Hewitt W R, Grewal H P, Nguyen J H, Hughes C B
Department of Transplantation Mayo Clinic Florida, Jacksonville, FL, USA.
Transplant Proc. 2009 Nov;41(9):3769-71. doi: 10.1016/j.transproceed.2009.05.043.
Adult polycystic liver disease (PLD) can cause massive hepatomegaly leading to pain, caval obstruction, and hemorrhage. Many surgical techniques including aspiration, fenestration, and resection have been used to treat PLD. In addition to substantial morbidity and mortality, conservative surgery may have limited success, and palliation may be temporary. With improved results of liver transplantation, it has become the definitive treatment for PLD. We retrospectively reviewed our experience in patients with PLD between 1998 and 2007. Thirteen patients underwent liver only or liver-kidney transplantation. All surgical procedures were performed with preservation of the recipient inferior vena cava and without venovenous bypass (piggyback technique). Our patients experienced a high rate of perioperative morbidity. However, long-term patient and graft survival were excellent.
成人多囊肝疾病（PLD）可导致肝脏大量肿大，引起疼痛、腔静脉阻塞和出血。包括穿刺抽吸、开窗引流和切除术在内的多种外科技术已被用于治疗PLD。除了较高的发病率和死亡率外，保守手术可能效果有限，且缓解可能是暂时的。随着肝移植效果的改善，它已成为PLD的确定性治疗方法。我们回顾性分析了1998年至2007年间我们治疗PLD患者的经验。13例患者接受了单纯肝移植或肝肾联合移植。所有手术均在保留受体下腔静脉且无静脉-静脉转流（背驮式技术）的情况下进行。我们的患者围手术期发病率较高。然而，患者和移植物的长期生存率良好。
