Department of Microbiology and Immunology, University of Illinois at Chicago, Chicago, IL 60612-7344, USA.
Cell Host Microbe. 2009 Nov 19;6(5):400-2. doi: 10.1016/j.chom.2009.10.009.
Riboswitches are RNA structures traditionally viewed as acting in cis to regulate downstream gene expression in bacteria. In a recent issue of Cell, Loh and colleagues report on the ability of a riboswitch to act in trans to modulate the expression of a critical bacterial virulence regulator.
Riboswitches 是传统上被视为在顺式作用以调节细菌下游基因表达的 RNA 结构。在最近一期的《Cell》杂志上，Loh 及其同事报道了一个 riboswitch 能够在反式作用中调节关键细菌毒力调节因子的表达的能力。
