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以巨大肾脏为表现的血管免疫母细胞性T细胞淋巴瘤:一例报告

Angioimmunoblastic T-cell lymphoma presenting as giant kidneys: a case report.

作者信息

Argov Ori, Charach Gideon, Weintraub Moshe, Shtabsky Alexander

出版信息

J Med Case Rep. 2009 Sep 14;3:9258. doi: 10.4076/1752-1947-3-9258.

Abstract

INTRODUCTION

Angioimmunoblastic T-cell lymphoma is a rare form of tumor of the lymph nodes or lymphoid tissue. In this report we describe an unusual presentation of angioimmunoblastic T-cell lymphoma consisting of giant kidneys with no nephrotic syndrome.

CASE PRESENTATION

A 46-year-old Arabic man from Gaza was hospitalized in our ward due to abdominal pain and a weight loss of 20 kg during the preceding two months. The results of the physical examination and laboratory tests raised the possibility of neoplastic disease. A computerized tomographic scan of the abdomen showed huge kidneys, and a kidney biopsy showed infiltration by lymphocytes and eosinophils. The genetic examination revealed T-cell lymphoma. Diagnosis was made by a lymph node biopsy, which shows typical findings of angioimmunoblastic T-cell lymphoma.

CONCLUSIONS

Angioimmunoblastic T-cell lymphoma can present with huge kidneys without nephrotic syndrome.

摘要

引言

血管免疫母细胞性T细胞淋巴瘤是一种罕见的淋巴结或淋巴组织肿瘤形式。在本报告中,我们描述了血管免疫母细胞性T细胞淋巴瘤的一种不寻常表现,即出现巨大肾脏且无肾病综合征。

病例介绍

一名来自加沙的46岁阿拉伯男子因腹痛和前两个月体重减轻20公斤而入住我们病房。体格检查和实验室检查结果提示存在肿瘤性疾病的可能性。腹部计算机断层扫描显示肾脏巨大,肾脏活检显示淋巴细胞和嗜酸性粒细胞浸润。基因检查显示为T细胞淋巴瘤。通过淋巴结活检确诊,其显示出血管免疫母细胞性T细胞淋巴瘤的典型表现。

结论

血管免疫母细胞性T细胞淋巴瘤可表现为巨大肾脏且无肾病综合征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22b7/2767156/8e5664fe27e5/1752-1947-0003-0000009258-1.jpg

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