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诊断难题:一例表现为骨髓非干酪样肉芽肿的血管免疫母细胞性T细胞淋巴瘤罕见病例

Diagnostic Dilemma: An Unusual Case of Angioimmunoblastic T-Cell Lymphoma Manifesting as Bone Marrow Non-Caseating Granuloma.

作者信息

Bhatlapenumarthi Vineel, Patwari Anannya, Pascual Sheila Karina

机构信息

Northern Light Eastern Maine Medical Center, 489 State Street, Bangor, ME 04401, USA.

Northern Light Cancer Care, 33 Whiting Hill Road, Brewer, ME 04412, USA.

出版信息

J Hematol. 2020 Apr;9(1-2):37-40. doi: 10.14740/jh607. Epub 2020 Apr 23.

Abstract

We present here a rare and unusual presentation of angioimmunoblastic T-cell lymphoma with non-necrotizing granuloma of bone marrow. We did not find any case reports of such case in our literature search. A 77-year-old man presented with shortness of breath, generalized weakness, fatigue and weight loss. Laboratory data revealed elevated white count, low platelets and anemia. Imaging studies revealed generalized lymphadenopathy. A bone marrow biopsy showed hypercellular marrow with non-caseating granuloma which was non-diagnostic and lymph node biopsy showed angioimmunoblastic T-cell lymphoma.

摘要

我们在此呈现一例罕见的血管免疫母细胞性T细胞淋巴瘤伴骨髓非坏死性肉芽肿的病例。在文献检索中,我们未发现此类病例的任何报道。一名77岁男性患者出现呼吸急促、全身乏力、疲劳和体重减轻症状。实验室检查数据显示白细胞计数升高、血小板减少和贫血。影像学检查显示全身淋巴结肿大。骨髓活检显示骨髓细胞增多伴非干酪样肉芽肿,该结果无诊断意义,而淋巴结活检显示为血管免疫母细胞性T细胞淋巴瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5467/7188380/92c32c908ae2/jh-09-037-g001.jpg

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