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前列腺癌筛查：欧洲随机前列腺癌筛查研究（ERSPC）和前列腺、肺癌、结直肠癌和卵巢癌筛查试验（PLCO）综述

Screening for Prostate Cancer: A Review of the ERSPC and PLCO Trials.

作者信息

Eckersberger Elisabeth, Finkelstein Julia, Sadri Helen, Margreiter Markus, Taneja Samir S, Lepor Herbert, Djavan Bob

机构信息

Department of Urology, School of Medicine, New York University New York, NY.

出版信息

Rev Urol. 2009 Summer;11(3):127-33.

PMID:19918338
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2777060/
Abstract

The advent of prostate-specific antigen (PSA) testing in the early 1980s revolutionized the diagnosis of prostate cancer. As a result of PSA testing, there has been a surge in the number of prostate cancer diagnoses. This review examines the results of 2 recent landmark trials that studied the effect of screening on prostate cancer mortality: the European Randomized Study of Screening for Prostate Cancer (ERSPC) and the US-based Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial.

摘要

20世纪80年代初前列腺特异性抗原（PSA）检测的出现彻底改变了前列腺癌的诊断方式。由于PSA检测，前列腺癌的诊断数量激增。本综述考察了两项近期具有里程碑意义的试验结果，这两项试验研究了筛查对前列腺癌死亡率的影响：欧洲前列腺癌筛查随机研究（ERSPC）和美国的前列腺、肺、结肠和卵巢（PLCO）癌筛查试验。

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本文引用的文献

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Annual screening for prostate cancer did not reduce mortality from prostate cancer.前列腺癌年度筛查并未降低前列腺癌死亡率。
Evid Based Med. 2009 Aug;14(4):104-5. doi: 10.1136/ebm.14.4.104.
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Prospective longitudinal comparative study of health-related quality of life in patients treated with radical prostatectomy or permanent brachytherapy for prostate cancer.前列腺癌根治性前列腺切除术或永久性近距离放射治疗患者健康相关生活质量的前瞻性纵向比较研究。
Acta Med Okayama. 2009 Jun;63(3):129-35. doi: 10.18926/AMO/31847.
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Prostate cancer: to screen or not to screen?前列腺癌：筛查还是不筛查？
Nat Rev Urol. 2009 Jun;6(6):299-301. doi: 10.1038/nrurol.2009.92.
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Cumulative incidence of false-positive results in repeated, multimodal cancer screening.重复多模式癌症筛查中假阳性结果的累积发生率。
Ann Fam Med. 2009 May-Jun;7(3):212-22. doi: 10.1370/afm.942.
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Screening and prostate-cancer mortality in a randomized European study.一项欧洲随机研究中的筛查与前列腺癌死亡率
N Engl J Med. 2009 Mar 26;360(13):1320-8. doi: 10.1056/NEJMoa0810084. Epub 2009 Mar 18.
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Mortality results from a randomized prostate-cancer screening trial.一项前列腺癌随机筛查试验的死亡率结果。
N Engl J Med. 2009 Mar 26;360(13):1310-9. doi: 10.1056/NEJMoa0810696. Epub 2009 Mar 18.
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Am J Med. 2004 Nov 15;117(10):719-25. doi: 10.1016/j.amjmed.2004.06.036.
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Cancer progression and survival rates following anatomical radical retropubic prostatectomy in 3,478 consecutive patients: long-term results.3478例连续性患者接受耻骨后根治性前列腺切除术后的癌症进展和生存率：长期结果
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Preventing cancer, cardiovascular disease, and diabetes: a common agenda for the American Cancer Society, the American Diabetes Association, and the American Heart Association.预防癌症、心血管疾病和糖尿病：美国癌症协会、美国糖尿病协会和美国心脏协会的共同议程。
Circulation. 2004 Jun 29;109(25):3244-55. doi: 10.1161/01.CIR.0000133321.00456.00. Epub 2004 Jun 15.
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