Tyritzis Stavros I, Adamakis Ioannis, Migdalis Vasileios, Vlachodimitropoulos Dimitrios, Constantinides Constantinos A
Department of Urology, Athens University Medical School, “LAIKO” Hospital, 17 Agiou Thoma str., Athens, 11527, Greece.
Cases J. 2009 Sep 1;2:8863. doi: 10.4076/1757-1626-2-8863.
Adrenal myelolipomas are relatively rare, non-functioning benign tumours composed of mature fatty and active hematopoietic elements. They can be asymptomatic, even if their size is massive. Diagnosis is relatively simple using ultrasound, computed tomography and magnetic resonance imaging. Surgical resection through an extraperitoneal approach is advocated in cases of symptomatic or large myelolipomas exceeding 5-cm in diameter. Their low incidence seems to be increasing from 0.2% to 10% during the last decade.
We present a case of a giant adrenal myelolipoma in a 68-year-old Caucasian male, who was presented with left lumbar pain. Renal ultrasound, CT and MRI demonstrated a well demarcated mass, with a maximum diameter of 10-cm. The differential diagnosis comprised the adrenal myelolipoma, the retroperitoneal liposarcoma and the renal angiomyolipoma. Thus, the patient was subjected to a left adrenalectomy.
Multiple theories have been proposed for the increasing frequency and natural course of the adrenal myelolipoma, with chronic adrenal stimulation and the contemporary stressful lifestyle to be the most appealing. Surgical treatment is advocated through an extraperitoneal approach because of the quicker recovery of the patient and the smaller postoperative complication rate.
肾上腺髓质脂肪瘤是相对罕见的无功能良性肿瘤,由成熟脂肪组织和活跃造血成分构成。即便瘤体巨大,它们也可能无症状。借助超声、计算机断层扫描和磁共振成像进行诊断相对简单。对于有症状的或直径超过5厘米的较大髓质脂肪瘤,主张通过腹膜外途径进行手术切除。在过去十年中,其低发病率似乎从0.2%增至10%。
我们报告一例68岁白种男性巨大肾上腺髓质脂肪瘤病例,该患者表现为左腰部疼痛。肾脏超声、CT和MRI显示一个边界清晰的肿块,最大直径为10厘米。鉴别诊断包括肾上腺髓质脂肪瘤、腹膜后脂肪肉瘤和肾血管平滑肌脂肪瘤。因此,该患者接受了左肾上腺切除术。
针对肾上腺髓质脂肪瘤发病率增加及其自然病程,已提出多种理论,其中慢性肾上腺刺激和现代紧张的生活方式最具说服力。由于患者恢复更快且术后并发症发生率更低,主张通过腹膜外途径进行手术治疗。