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脉冲式泼尼松龙治疗后出现胸痛和麻痹:甲状腺毒症性周期性麻痹的罕见病例报告

Chest pain and paralysis after pulse prednisolone therapy an unusual case presentation of thyrotoxic periodic paralysis: a case report.

作者信息

Hagel Stefan, Elznerova Tereza, Dietrich Wenke, Schrauzer Thomas, John Stefan

机构信息

Department of Nephrology and Hypertension, University Hospital Erlangen-Nuremberg, Breslauerstrasse 201, 90471 Nuremberg,Germany.

出版信息

Cases J. 2009 Aug 25;2:7501. doi: 10.4076/1757-1626-2-7501.

Abstract

Thyrotoxic periodic paralysis is a disease characterized by recurrent episodes of paralysis and hypokalemia during a thyrotoxic state. Thyrotoxic periodic paralysis is a common complication of hyperthyroidism in Asian populations, but can affect other ethnic groups as well. Due to population mobility, Thyrotoxic periodic paralysis is increasingly common in Western countries. Early diagnosis and prompt treatment of the thyrotoxic state and potassium supplementation prevent life-threatening complications associated with hypokalemia and muscle weakness. We present a young Turkish man who developed acute flaccid paralysis after receiving pulse prednisolone therapy for treatment of Pityriasis versicolor. His muscle strength and serum potassium fully recovered after potassium replacement and treatment of the thyrotoxic state which was a consequence of underlying Graves' disease.

摘要

甲状腺毒症性周期性瘫痪是一种在甲状腺毒症状态下以反复发作的瘫痪和低钾血症为特征的疾病。甲状腺毒症性周期性瘫痪是亚洲人群甲状腺功能亢进症的常见并发症,但也可影响其他种族群体。由于人口流动,甲状腺毒症性周期性瘫痪在西方国家越来越常见。对甲状腺毒症状态进行早期诊断和及时治疗以及补充钾可预防与低钾血症和肌肉无力相关的危及生命的并发症。我们报告一名年轻的土耳其男性,他在接受脉冲泼尼松龙治疗花斑糠疹后出现急性弛缓性瘫痪。在补充钾并治疗由潜在的格雷夫斯病导致的甲状腺毒症状态后,他的肌肉力量和血清钾完全恢复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9aff/2769357/1124e9e60f1f/1757-1626-0002-0000007501-001.jpg

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