Henninger Benjamin, Freund Martin, Zelger Bettina, Putzer Daniel, Bonatti Hugo, Müller Ludwig, Fiegl Michael, Geltner Christian
Department of Radiology, Innsbruck Medical University, Anichstraße 35, 6020 Innsbruck, Austria.
Cases J. 2009 Aug 7;2:6948. doi: 10.4076/1757-1626-2-6948.
Primary mediastinal synovial sarcoma is a rare malignancy with only a few cases reported so far. A 56-year-old woman was admitted to our hospital for an investigation of a nodule in the left middle lung on chest radiography. Computed tomography revealed a mediastinal mass first described as a solitary fibrous tumor. The diagnosis of synovial sarcoma was established by computed tomography-guided percutaneous needle biopsy. Work up showed no metastasis to distant organs or contralateral pleural cavity. The mass was surgically resected; pathological and immunohistochemical analyses confirmed the diagnosis of a monophasic spindle cell synovial sarcoma probably originating from phrenic nerve. The patient received adjuvant chemotherapy and radiation and is free of recurrence after a follow up of 16 months.
原发性纵隔滑膜肉瘤是一种罕见的恶性肿瘤，迄今为止仅有少数病例报道。一名56岁女性因胸部X线检查发现左肺中叶结节而入院。计算机断层扫描显示一个纵隔肿块，最初被描述为孤立性纤维瘤。通过计算机断层扫描引导下经皮穿刺活检确诊为滑膜肉瘤。检查显示无远处器官或对侧胸腔转移。该肿块接受了手术切除；病理和免疫组化分析证实诊断为单相梭形细胞滑膜肉瘤，可能起源于膈神经。患者接受了辅助化疗和放疗，随访16个月后无复发。
