无糖尿病病史患者的结节性肾小球硬化：一例报告
Nodular glomerulosclerosis in patients' without history of diabetes mellitus: a case report.
作者信息
Helal Imed, Goucha Rym, Karoui Cyrine, Abderrahim Ezzedine, Hamida Fethi Ben, Elyounsi Fethi, Maiz Hedi Ben, Abdallah Taieb Ben, Kheder Adel
机构信息
Department of Internal Medicine A and Laboratory of Kidney Pathology 02, Charles Nicolle Hospital Boulevard 9 Avril. 1006 Tunis Tunisia.
出版信息
Cases J. 2009 Sep 16;2:6792. doi: 10.4076/1757-1626-2-6792.
INTRODUCTION
Diabetic nephropathy can occur during the course of both type1 and type 2 diabetes mellitus. The characteristic lesions are diffuse or nodular (Kimmelsteil-Wilson) diabetic glomerulosclerosis. The reported cases represent unusual presentations of diabetes mellitus.
CASE PRESENTATION
We report the case of a 49-year-old man without prior history of diabetes mellitus who presented with rapidly progressive renal failure and whose renal biopsy revealed nodular (Kimmelsteil-Wilson) glomerulosclerosis lesions characteristic of diabetes.
CONCLUSION
Renal manifestations of diabetes mellitus may antedate other more common presenting symptoms of this disease and we critically review the literature on this subject.
引言
1型和2型糖尿病病程中均可发生糖尿病肾病。其特征性病变为弥漫性或结节性（金梅尔施泰因－威尔逊病变）糖尿病肾小球硬化症。所报告的病例代表了糖尿病的不寻常表现。
病例介绍
我们报告了一名49岁男性病例，该患者既往无糖尿病病史，表现为快速进展性肾衰竭，肾活检显示具有糖尿病特征性的结节性（金梅尔施泰因－威尔逊病变）肾小球硬化症病变。
结论
糖尿病的肾脏表现可能先于该疾病其他更常见的症状出现，我们对该主题的文献进行了批判性综述。
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