Uchimura Nelson Shozo, Nakano Keiji, Nakano Lina Cavalcanti de Góes, Uchimura Taqueco Teruya
Universidade Estadual de Maringá, Maringá, PR.
Rev Assoc Med Bras (1992). 2009 Sep-Oct;55(5):569-74. doi: 10.1590/s0104-42302009000500021.
To estimate prevalence and analyze quality and performance of colpocytology carried out under the Cervical Cancer Screening Program in Maringá, Paraná, Brazil.
A retrospective study of the SIS-Colo database of the Brazilian Ministry of Health. Variables such as age, colpocytology result and origin were analyzed. Ages were divided into brackets; origin was distributed in five Regional Health Divisions of the city of Maringá; colpocytology was categorized according to the Bethesda System. Colpocytology, coverage was calculated by dividing the number of exams in the population between 25 and 59 years of age by the number of women in that same age group.
The 17,664 colpocytology exams collected in 2005 by the public health system were distributed among women between 12 and 82 years of age, with 12,961 (73.4%) examinations in women between the ages of 25 and 59, considered at high risk for cancer. A total of 17,458 (98.84%) cytological examinations were negative for malignancy, and atypical results (ASCUS / AGUS, LSIL, HSIL and invasive cancer) totaled 206 (1.16%). The study found a prevalence of 0.85% (151) for ASCUS / AGUS, 1.14% (203/17.664) for atypical cells, and a 2.75 ASCUS / atypical cells ratio (151/55).
The lower than expected prevalence of colpocytological and ASCUS alterations, the high ASCUS / atypical cells ratio and the insufficient population coverage by colpocytology jeopardized the performance of the cervical cancer prevention program. The low-income population requires special attention, and those more privileged should be advised about the frequency of examination and the age bracket with higher risks.
评估巴西巴拉那州马林加市宫颈癌筛查项目下阴道细胞学检查的患病率，并分析其质量和执行情况。
对巴西卫生部SIS - Colo数据库进行回顾性研究。分析年龄、阴道细胞学检查结果和来源等变量。年龄分为若干年龄段；来源分布在马林加市的五个区域卫生部门；阴道细胞学检查根据贝塞斯达系统进行分类。通过将25至59岁人群中的检查次数除以该同一年龄组中的女性人数来计算阴道细胞学检查的覆盖率。
2005年公共卫生系统收集的17664例阴道细胞学检查分布在12至82岁的女性中，其中12961例（73.4%）检查是在25至59岁被认为患癌风险较高的女性中进行的。总共17458例（98.84%）细胞学检查恶性结果为阴性，非典型结果（意义不明确的非典型鳞状细胞/意义不明确的非典型腺细胞、低度鳞状上皮内病变、高度鳞状上皮内病变和浸润癌）共计206例（1.16%）。该研究发现意义不明确的非典型鳞状细胞/意义不明确的非典型腺细胞的患病率为0.85%（151例），非典型细胞的患病率为1.14%（203/17664），意义不明确的非典型鳞状细胞/非典型细胞比例为2.75（...）。
阴道细胞学检查和意义不明确的非典型鳞状细胞改变的患病率低于预期，意义不明确的非典型鳞状细胞/非典型细胞比例较高以及阴道细胞学检查的人群覆盖率不足危及了宫颈癌预防项目的执行情况。低收入人群需要特别关注，而那些条件较好的人群应被告知检查频率和风险较高的年龄段。 （注：原文中“2.75 ASCUS / atypical cells ratio (151/55)”括号内“55”未明确说明是什么数据，翻译时保留原文形式）
