Penfold Chris M, Thomas Steven J, Waylen Andrea, Ness Andrew R
National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol NHS Foundation Trust and University of Bristol, Bristol, UK.
School of Oral and Dental Sciences, University of Bristol, Bristol, UK.
Head Neck. 2018 Jul;40(7):1389-1399. doi: 10.1002/hed.25116. Epub 2018 Feb 27.
Tobacco and alcohol consumption are risk factors for developing head and neck cancer, and continuation postdiagnosis can adversely affect prognosis. We explored changes to these behaviors after a head and neck cancer diagnosis.
Demographic and clinical data were collected from 973 people newly diagnosed with oral cavity, oropharyngeal, or laryngeal cancer. Tobacco and alcohol consumption were additionally collected 4 and 12 months later.
The prevalence of high alcohol consumption reduced from 54.3% at diagnosis to 41.4% at 12 months, and smoking reduced from 21.0% to 11.7%. Changes in behavior were dynamic, for example, 44% of smokers at 12 months were not smoking at diagnosis or 4 months. Several factors were associated with alcohol consumption, whereas only tumor site and comorbidities were associated with smoking.
A diagnosis of head and neck cancer can result in important changes in alcohol consumption and smoking prevalence. However, these changes are dynamic in the first year after diagnosis.
烟草和酒精消费是头颈癌发病的危险因素，确诊后继续使用会对预后产生不利影响。我们探讨了头颈癌确诊后这些行为的变化。
收集了973例新诊断为口腔癌、口咽癌或喉癌患者的人口统计学和临床数据。在4个月和12个月后额外收集了烟草和酒精消费情况。
高酒精消费率从确诊时的54.3%降至12个月时的41.4%，吸烟率从21.0%降至11.7%。行为变化是动态的，例如，12个月时的吸烟者中有44%在确诊时或4个月时不吸烟。几个因素与酒精消费有关，而只有肿瘤部位和合并症与吸烟有关。
头颈癌诊断可导致酒精消费和吸烟率发生重要变化。然而，这些变化在确诊后的第一年是动态的。
