Center for Complex and Nonlinear Systems and the Department of Physics, Budapest University of Technology and Economics, H-1521 Budapest, Hungary.
J Phys Chem A. 2009 Dec 24;113(51):14095-8. doi: 10.1021/jp907364a.
It was found that the inhibitory effect of resorcinol is less pronounced if it is added in a later stage of the Briggs-Rauscher reaction, which indicates that an accumulating intermediate--most probably iodomalonic acid--can suppress the inhibition. In fact, when iodomalonic acid was added to the reaction mixture, the inhibitory period was shortened considerably even at micromolar levels of the iodomalonic acid concentration. Moreover, iodomalonic acid can accelerate the rate of the reaction when applied in the same low concentrations, suggesting that it can be an autocatalytic intermediate of the Briggs-Rauscher reaction.
研究发现，如果间苯二酚在 Briggs-Rauscher 反应的后期添加，其抑制作用则不那么明显，这表明一种积累性的中间产物（很可能是碘代丙二酸）可以抑制这种抑制作用。事实上，当将碘代丙二酸添加到反应混合物中时，即使在碘代丙二酸浓度为微摩尔级的情况下，抑制期也会大大缩短。此外，当以相同的低浓度使用时，碘代丙二酸可以加速反应速率，这表明它可以是 Briggs-Rauscher 反应的自催化中间产物。
