Acquaviva Eric, Legleye Stéphane, Auleley Guy R, Deligne Jean, Carel Didier, Falissard B Bruno
Inserm U669, PSIGIAM, Paris, France.
BMC Psychiatry. 2009 Nov 17;9:72. doi: 10.1186/1471-244X-9-72.
The aim of this work is to estimate the French frequencies of dispensed psychotropic prescriptions in children and adolescents. Prevalence estimations of dispensed prescriptions are compared to the frequencies of use of psychotropic reported by 17 year-old adolescents.
Prescription data is derived from national health insurance databases. Frequencies of dispensed prescriptions are extrapolated to estimate a range for the 2004 national rates. Self-report data is derived from the 2003 and 2005 ESCAPAD study, an epidemiological study based on a questionnaire focused on health and drug consumption.
The prevalence estimation shows that the prevalence of prescription of a psychotropic medication to young persons between 3 and 18 years is about 2.2%.In 2005, the self-report study (ESCAPAD) shows that 14.9% of 17 year-old adolescents took medication for "nerves" or "to sleep" during the previous 12 months. The same study in 2003 also shows that 62.3% of adolescents aged 17 and 18 reporting psychotropic use, took the medication for anxiety and 56.8% to sleep. Only 49.7% of these medications are suggested by a doctor.
This study underlines a similar range of prevalence of psychotropic prescriptions in France to that observed in other European countries. Nevertheless, the proportion of antipsychotics and benzodiazepines seems to be higher, whereas the proportion of methylphenidate is lower.Secondly, a disparity between the prevalence of dispensed prescriptions and the self-report of actual use of psychotropics has been highlighted by the ESCAPAD study which shows that these treatments are widely used as "self-medication".
本研究旨在估算法国儿童及青少年中精神类药物处方的配药频率。将配药处方的患病率估计值与17岁青少年报告的精神类药物使用频率进行比较。
处方数据源自国家医疗保险数据库。通过外推配药处方频率来估算2004年全国患病率范围。自我报告数据源自2003年和2005年的ESCAPAD研究,这是一项基于关注健康和药物消费的问卷的流行病学研究。
患病率估计显示,3至18岁青少年中精神类药物处方的患病率约为2.2%。2005年,自我报告研究(ESCAPAD)显示,14.9%的17岁青少年在过去12个月内服用过治疗“神经紧张”或“助眠”的药物。2003年的同一项研究还显示,17岁和18岁报告使用精神类药物的青少年中,62.3%是为了缓解焦虑而服药,56.8%是为了助眠。这些药物中只有49.7%是由医生建议使用的。
本研究强调法国精神类药物处方的患病率范围与其他欧洲国家观察到的相似。然而,抗精神病药物和苯二氮䓬类药物的比例似乎更高,而哌甲酯的比例更低。其次,ESCAPAD研究突出了配药处方患病率与精神类药物实际使用自我报告之间的差异,该研究表明这些治疗方法被广泛用作“自我用药”。