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初级保健中急性痛风就诊后的处方和合并症筛查。

Prescription and comorbidity screening following consultation for acute gout in primary care.

机构信息

Arthritis Research Campaign National Primary Care Centre, Primary Care Sciences, Keele University, Keele, Staffordshire ST5 5BG, UK.

出版信息

Rheumatology (Oxford). 2010 Jan;49(1):105-11. doi: 10.1093/rheumatology/kep332. Epub 2009 Nov 17.

Abstract

OBJECTIVE

To describe prescribing patterns and cardiovascular risk factor screening in patients, following consultation for acute gout in primary care.

METHODS

This study was undertaken in two inter-linked regional primary care databases: Consultations in Primary Care Archive (CiPCA) and Prescriptions in Primary Care Archive (PiPCA). During 2001-04, consultations in CiPCA were identified at 10 participating practices from gout-related Read morbidity codes. Lipid, blood pressure, glucose and renal function monitoring were identified from Read codes and consultation free text over the next month. Prescriptions for traditional NSAIDs, gastroprotective agents, colchicine, coxibs, corticosteroids, analgesic agents and urate-lowering therapies (ULTs) issued to these patients over the subsequent 12 months were identified from PiPCA.

RESULTS

Six hundred and seventy-three new gout consultations were identified. Monitoring of lipids (5%), blood pressure (26%), glucose (6%) and renal function (21%) within 1 month of index consultation were infrequently recorded. There were 583 consultations for acute gout. Traditional NSAIDs (68%) were most commonly prescribed, followed by colchicine (15%), coxibs (5%) and analgesia only (5%). Seven per cent did not receive a prescription. The most frequently prescribed traditional NSAIDs were diclofenac (41%) and indomethacin (32%). Gastroprotection was co-prescribed with NSAIDs for 17% of patients. Sixty six per cent of patients treated with colchicine were prescribed high-dose regimens (500 microg at least four times daily). ULTs were prescribed within 12 months in 23% of patients. Nineteen per cent of ULTs were prescribed during acute attack.

CONCLUSIONS

Primary care acute gout management is suboptimal. Education of general practitioners about acute gout management and cardiovascular risk is a priority.

摘要

目的

描述在初级保健中,急性痛风患者就诊后的处方模式和心血管风险因素筛查情况。

方法

本研究在两个相互关联的区域初级保健数据库中进行:初级保健咨询档案(CiPCA)和初级保健处方档案(PiPCA)。在 2001-04 年期间,从与痛风相关的 Read 发病代码中确定了 CiPCA 中 10 个参与实践的会诊。在下一个月内,通过 Read 代码和会诊自由文本识别血脂、血压、血糖和肾功能监测情况。在随后的 12 个月内,从 PiPCA 中确定了为这些患者开出的传统非甾体抗炎药、胃保护剂、秋水仙碱、COXIBs、皮质类固醇、镇痛药和尿酸降低疗法(ULTs)的处方。

结果

共确定了 673 例新的痛风会诊。在指数会诊后 1 个月内,对血脂(5%)、血压(26%)、血糖(6%)和肾功能(21%)的监测记录较少。有 583 例急性痛风的会诊。传统非甾体抗炎药(68%)最常被开处方,其次是秋水仙碱(15%)、COXIBs(5%)和仅使用镇痛药(5%)。有 7%的患者没有开处方。最常开的传统 NSAIDs 是双氯芬酸(41%)和吲哚美辛(32%)。有 17%的患者同时使用 NSAIDs 和胃保护剂。有 66%的使用秋水仙碱的患者开了高剂量方案(至少每日 4 次,每次 500 微克)。在 12 个月内,有 23%的患者开了 ULTs。19%的 ULTs在急性发作期间开处方。

结论

初级保健急性痛风管理不佳。对全科医生进行急性痛风管理和心血管风险教育是当务之急。

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