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痛风相关性肾损伤的危险因素及早期诊断生物标志物的研究进展。

Research progress of risk factors and early diagnostic biomarkers of gout-induced renal injury.

机构信息

Shanxi Bethune Hospital, Shanxi Medical University, Taiyuan, China.

Department of Rheumatology, Shanxi Bethune Hospital, Shanxi Medical University, Taiyuan, China.

出版信息

Front Immunol. 2022 Sep 20;13:908517. doi: 10.3389/fimmu.2022.908517. eCollection 2022.

Abstract

Gout renal injury has an insidious onset, no obvious symptoms, and laboratory abnormalities in the early stages of the disease. The injury is not easily detected, and in many cases, the patients have entered the renal failure stage at the time of diagnosis. Therefore, the detection of gout renal injury-related risk factors and early diagnostic biomarkers of gout renal injury is essential for the prevention and early diagnosis of the disease. This article reviews the research progress in risk factors and early diagnostic biomarkers of gout renal injury.

摘要

痛风性肾病损伤起病隐匿,早期无明显症状和实验室异常,损伤不易被察觉,很多情况下患者在诊断时已进入肾衰竭阶段。因此,检测痛风性肾病损伤的相关危险因素和早期诊断生物标志物对于疾病的预防和早期诊断至关重要。本文就痛风性肾病损伤的危险因素和早期诊断生物标志物的研究进展作一综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62f4/9530830/1c87a0e62cf1/fimmu-13-908517-g001.jpg

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