Department of Medicine and Geriatrics, Tai Po Hospital, HKSAR, 9 Chuen On Road, Tai Po, NT, Hong Kong SAR.
Rheumatology (Oxford). 2010 Jan;49(1):112-5. doi: 10.1093/rheumatology/kep348. Epub 2009 Nov 17.
To evaluate and validate the Classification of Psoriatic Arthritis (CASPAR) criteria for PsA in a Chinese population.
Data were collected prospectively from consecutive Han Chinese clinic attendees with PsA and other chronic inflammatory arthritis. Subjects were classified according to Moll and Wright, European Spondyloarthropathy Study Group (ESSG) criteria for PsA, Vasey and Espinoza or CASPAR criteria. Sensitivity and specificity of each set of criteria were compared with the expert clinical diagnosis. Latent class analysis was used to calculate accuracy of criteria and confirm validity.
A total of 108 (53 males and 55 females) subjects with PsA were recruited. Mean (s.d.) age and duration of illness were 48.4 (12.0) and 9.55 (7.66) years, respectively. Data were compared with 195 controls with RA (n = 154) and AS (n = 41). The ESSG criteria have the lowest sensitivity, followed by the Moll and Wright criteria. The sensitivity and specificity for the CASPAR criteria were 98.2 and 99.5%, respectively, which is similar to reported values in European populations. The latent class model agreed closely with the clinical criteria.
The CASPAR criteria performed well in a Chinese population, which is very different from the populations for which they were developed. The CASPAR criteria have higher sensitivity in classifying PsA.
评估和验证分类银屑病关节炎（CASPAR）标准在中国人群中的银屑病关节炎（PsA）。
前瞻性收集来自汉族连续门诊的银屑病关节炎和其他慢性炎症性关节炎患者的数据。根据莫尔和赖特、欧洲脊柱关节病研究组（ESSG）标准、Vasey 和 Espinoza 或 CASPAR 标准对患者进行分类。比较每组标准与专家临床诊断的敏感性和特异性。采用潜在类别分析计算标准的准确性并确认其有效性。
共纳入 108 例（男性 53 例，女性 55 例）银屑病关节炎患者。平均（标准差）年龄和病程分别为 48.4（12.0）和 9.55（7.66）年。数据与 195 例类风湿关节炎（n=154）和强直性脊柱炎（n=41）对照进行比较。ESSG 标准的敏感性最低，其次是 Moll 和 Wright 标准。CASPAR 标准的敏感性和特异性分别为 98.2%和 99.5%，与欧洲人群的报道值相似。潜在类别模型与临床标准密切一致。
CASPAR 标准在中国人群中表现良好，与开发它们的人群有很大不同。CASPAR 标准在分类银屑病关节炎方面具有更高的敏感性。
