银屑病关节炎分类标准：莫尔与赖特标准、欧洲脊柱关节病研究组标准和CASPAR标准——一项比较研究。

Psoriatic arthritis classification criteria: Moll and Wright, ESSG and CASPAR -- a comparative study.

作者信息

Zlatkovic-Svenda Mirjana, Kerimovic-Morina Djunajder, Stojanovic Roksanda M

出版信息

Acta Reumatol Port. 2013 Jul-Sep;38(3):172-8.

DOI:

PMID:24149013

Abstract

OBJECTIVES

to evaluate and compare Moll and Wright, ESSG and CASPAR criteria for psoriatic arthritis (PsA) classification.

PATIENTS AND METHODS

Study comprised 356 patients (pts): 120 PsA pts in the investigated group, 123 pts with rheumatoid arthritis (RA) and 113 pts with non-inflammatory musculoskeletal symptoms (NIMS) in two control groups. Clinical diagnosis was the gold standard. Moll and Wright, ESSG and CASPAR criteria were applied to all pts. Sensitivity was calculated for each of the classification criteria sets; specificity was assessed in relation to RA and to NIMS groups, separately. Concordance between the investigated criteria sets was determined.

RESULTS

Sensitivity was 91.7% for CASPAR, 85.8% for Moll and Wright and 63.3% for ESSG criteria. Specificity for Moll and Wright criteria was 100%, with relation to both RA and to NIMS group. Specificity of CASPAR criteria was 99.2% and 99.1%; specificity of ESSG criteria was 94.3% and 67%, with regard to RA and to NIMS groups, respectively. Significant fair concordance was found only between CASPAR and Moll and Wright criteria (k=0.379 p<0.001).

CONCLUSIONS

The highest sensitivity had the CASPAR criteria, followed by Moll and Wright and ESSG. The highest specificity showed Moll and Wright criteria, followed by CASPAR and ESSG. CASPAR criteria demonstrated high specificity when applied to both NIMS and RA group. The lowest specificity was found for the ESSG criteria in relation to NIMS group. The only significant concordance was shown between CASPAR and Moll and Wright criteria.

摘要

目的

评估并比较用于银屑病关节炎（PsA）分类的莫尔（Moll）和赖特（Wright）标准、欧洲脊柱关节病研究组（ESSG）标准和分类标准评估银屑病关节炎（CASPAR）标准。

患者与方法

研究纳入356例患者：研究组中有120例PsA患者，两个对照组中有123例类风湿关节炎（RA）患者和113例非炎性肌肉骨骼症状（NIMS）患者。临床诊断为金标准。对所有患者应用莫尔和赖特标准、ESSG标准及CASPAR标准。计算每个分类标准集的敏感性；分别针对RA组和NIMS组评估特异性。确定所研究的标准集之间的一致性。

结果

CASPAR标准的敏感性为91.7%，莫尔和赖特标准为85.8%，ESSG标准为63.3%。莫尔和赖特标准相对于RA组和NIMS组的特异性均为100%。CASPAR标准相对于RA组的特异性为99.2%，相对于NIMS组为99.1%；ESSG标准相对于RA组的特异性为94.3%，相对于NIMS组为67%。仅在CASPAR标准与莫尔和赖特标准之间发现显著的中等一致性（k = 0.379，p < 0.001）。