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因误服唑吡坦导致的短暂性全面遗忘样发作:老年人的药物安全性担忧。

Transient global amnesia-like episode due to mistaken intake of zolpidem: drug safety concern in the elderly.

机构信息

Department of Internal Medicine, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan, Republic of China.

出版信息

J Patient Saf. 2009 Mar;5(1):32-4. doi: 10.1097/PTS.0b013e3181990d62.

Abstract

OBJECTIVE

Chronic insomnia is a common phenomenon among the elderly. Inaccurate handling and use of hypnotics in the elderly has become an important issue in patient safety. Older people who self-medicate often have a high risk for medication errors.

METHODS AND RESULTS

We described here the case of a 65-year-old woman who experienced recurrent transient anterograde amnesia, anxiety, bewilderment, and repetitive questioning that lasted for 2 to 3 hours after erroneously taking zolpidem. This mistake was due to the similarity in appearance between zolpidem and her newly prescribed anticholesterol drug, ezetimibe.

CONCLUSIONS

History of medication, particularly as regards hypnotics, should be carefully reviewed when a patient presents with transient global amnesia-like symptoms. The inadvertent use of drugs may be an underrecognized phenomenon among the elderly who self-medicate. When prescribing a new drug to elderly patients, especially hypnotics, physicians and pharmacists should educate them and their families about the proper use of these medications for their own safety.

摘要

目的

慢性失眠在老年人中较为常见。老年人对催眠药物的处理和使用不当已成为患者安全的一个重要问题。自行用药的老年人经常存在用药错误的高风险。

方法和结果

我们在此描述了一位 65 岁女性的病例,她在错误服用唑吡坦后出现反复短暂顺行性遗忘、焦虑、困惑和重复提问,持续 2 至 3 小时。这一错误是由于唑吡坦和她新处方的降胆固醇药物依折麦布外观相似所致。

结论

当患者出现类似短暂性全面遗忘的症状时,应仔细审查用药史,尤其是催眠药物。自行用药的老年人中,药物的意外使用可能是一个未被充分认识的现象。当给老年患者,尤其是催眠药物时,医生和药剂师应教育他们及其家属正确使用这些药物以确保自身安全。

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