Department of Ophthalmology, Groote Schuur Hospital and University of Cape Town, Cape Town, South Africa.
J Glaucoma. 1993 Winter;2(4):285-90.
To examine the results and complications of trabeculectomy performed for advanced angle-closure glaucoma, a retrospective study was undertaken of 39 patients (46 eyes) who had chronic angle-closure glaucoma and who had undergone trabeculectomy during a 5-year period. The main indication for trabeculectomy was an inability to control the intraocular pressure with glaucoma medication. The surgery was not complicated by visual loss or malignant glaucoma. The intraocular pressure was successfully reduced to <21 mm Hg in 30 eyes (66.7%) without medication and in a further 11 eyes (24.4%) with additional topical glaucoma medication, after a mean follow-up period of 19 months. A second trabeculectomy was required in four patients (8.9%) (mean period: 35.8 months later) and a cataract extraction with intraocular lens implantation was required in nine patients (mean period: 23.9 months later). These results indicate that although trabeculectomy is effective and relatively safe in the management of advanced chronic angle-closure glaucoma, at least one in three patients will require a second operation within 3 years.
为了研究对晚期闭角型青光眼施行小梁切除术的结果和并发症，对 5 年间施行小梁切除术的 39 例（46 只眼）慢性闭角型青光眼患者进行了回顾性研究。施行小梁切除术的主要指征是药物不能控制眼压。手术未导致视力丧失或恶性青光眼等并发症。平均随访 19 个月后，30 只眼（66.7%）在不服药的情况下眼压成功降至<21mmHg，11 只眼（24.4%）在加用局部青光眼药物的情况下眼压成功降至<21mmHg。4 例患者（8.9%）需要再次施行小梁切除术（平均时间：35.8 个月后），9 例患者（平均时间：23.9 个月后）需要施行白内障摘除加人工晶状体植入术。这些结果表明，虽然小梁切除术对晚期慢性闭角型青光眼的治疗有效且相对安全，但至少有 1/3 的患者在 3 年内需要再次手术。
