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左炔诺孕酮宫内节育系统的安全性、有效性及患者可接受性综述。

Review of the safety, efficacy and patient acceptability of the levonorgestrel-releasing intrauterine system.

作者信息

Kailasam Chandra, Cahill David

机构信息

Bristol Centre for Reproductive Medicine, Southmead Hospital, Bristol, UK;

出版信息

Patient Prefer Adherence. 2008 Feb 2;2:293-302. doi: 10.2147/ppa.s3464.

Abstract

The levonorgestrel-containing intrauterine system is an extremely effective, reversible and safe form of long-term yet reversible birth control. In view of its efficacy, it is a safer alternative to permanent contraceptive methods such as sterilization. It is especially useful in situations where use of estrogen-containing contraceptives is contraindicated. While menstrual disturbances are a common side effect, proper counseling improves compliance. In addition to its contraceptive effect, the levonorgestrel intrauterine system offers potential therapeutic benefits in other clinical contexts, including menorrhagia, symptomatic fibroids, endometriosis, and endometrial protection.

摘要

含左炔诺孕酮宫内节育系统是一种极其有效、可逆且安全的长效可逆避孕方式。鉴于其有效性,它是绝育等永久性避孕方法的更安全替代方案。在禁忌使用含雌激素避孕药的情况下,它尤其有用。虽然月经紊乱是常见的副作用,但适当的咨询可提高依从性。除了避孕作用外,左炔诺孕酮宫内节育系统在其他临床情况下还具有潜在的治疗益处,包括月经过多、有症状的子宫肌瘤、子宫内膜异位症和子宫内膜保护。

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