Hernández F, Mata L, López M E, Lizano C
Bol Med Hosp Infant Mex. 1977 Sep-Oct;34(5):993-1000.
The study comprised 19 children with severe protein-calorie malnutrition admitted to Hospital Nacional de Niños. With one exception, all of the patients complained of diarrhea at the examination. Samples of stools were collected for bacteriologic, parasitologic and virologic studies. Rotavirus was shown in 4 cases and adenovirus in another 4. Enteropathogenic Escherichia coli, Shigella and Salmonella were isolated in 9 different children. It was possible to demonstrate at least one potentially pathogenic agent in 84% of the total number of cases. In malnourished infants under one year of age, the index of positiveness was 100%. It is set forth that infection is the most important factor in the etiology of diarrhea of the malnourished infant.
该研究纳入了19名入住国家儿童医院的重度蛋白质-热量营养不良儿童。除1例例外,所有患者在检查时均主诉有腹泻症状。采集粪便样本进行细菌学、寄生虫学和病毒学研究。4例检出轮状病毒,另4例检出腺病毒。9名不同儿童分离出致病性大肠杆菌、志贺氏菌和沙门氏菌。在所有病例中,84%的病例至少检出一种潜在病原体。在1岁以下的营养不良婴儿中,阳性率为100%。研究表明,感染是营养不良婴儿腹泻病因中最重要的因素。