Suppr超能文献

儿童银屑病的流行病学和共病情况。

Epidemiology and comorbidity of psoriasis in children.

机构信息

CVderm - German Center for Health Services Research in Dermatology, Department of Dermatology, University Clinics of Hamburg, Hamburg, Germany.

出版信息

Br J Dermatol. 2010 Mar;162(3):633-6. doi: 10.1111/j.1365-2133.2009.09593.x. Epub 2009 Nov 18.

Abstract

BACKGROUND

Psoriasis is a common disease affecting all age groups. In contrast to adult psoriasis, only few studies on the epidemiology of childhood psoriasis have been published.

OBJECTIVES

Assessment of prevalence and comorbidities of juvenile psoriasis in Germany based on health insurance data.

METHODS

Data were collected from a database of about 1.3 million nonselected individuals from a German statutory health insurance organization which covers all geographical regions. Individuals with psoriasis were identified by ICD-10 codes applied to all outpatient and inpatient visits. The present analysis consists of all patients who were enlisted throughout the year 2005. The diagnosis of psoriasis was registered whenever there was at least one documented patient contact using code L40.* and subcodes. Comorbidities were also evaluated by ICD-10 diagnoses.

RESULTS

In total, 33 981 patients with the diagnosis of psoriasis were identified. The prevalence in 2005 was 2.5%. The total rate of psoriasis in children younger than 18 years was 0.71%. The prevalence rates increased in an approximately linear manner from 0.12% at the age of 1 year to 1.2% at the age of 18 years. The overall rate of comorbidity in subjects with psoriasis aged under 20 years was twice as high as in subjects without psoriasis. Juvenile psoriasis was associated with increased rates of hyperlipidaemia, obesity, hypertension, diabetes mellitus, rheumatoid arthritis and Crohn disease.

CONCLUSIONS

Psoriasis is a common disease in children. Like in adults, it is associated with significant comorbidity. Increased attention should be paid to the early detection and treatment of patients affected.

摘要

背景

银屑病是一种常见的影响所有年龄段的疾病。与成人银屑病相比,仅有少数研究报道了儿童银屑病的流行病学。

目的

基于健康保险数据评估德国青少年银屑病的患病率和合并症。

方法

从德国法定健康保险机构的一个约 130 万非选择性个体的数据库中收集数据,该机构涵盖所有地理区域。通过应用于所有门诊和住院就诊的 ICD-10 代码来识别银屑病患者。本分析包括 2005 年全年登记的所有患者。只要使用代码 L40.*和子代码记录了至少一次有患者就诊的记录,就会诊断为银屑病。通过 ICD-10 诊断也评估了合并症。

结果

共确定了 33981 名患有银屑病的患者。2005 年的患病率为 2.5%。18 岁以下儿童银屑病的总发病率为 0.71%。患病率从 1 岁时的 0.12%大致呈线性增加到 18 岁时的 1.2%。20 岁以下患有银屑病的患者合并症的总体发生率是没有银屑病的患者的两倍。青少年银屑病与血脂异常、肥胖、高血压、糖尿病、类风湿关节炎和克罗恩病的发病率增加有关。

结论

银屑病在儿童中较为常见。与成人一样,它与显著的合并症相关。应更加关注受影响患者的早期发现和治疗。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验