魁北克青少年类风湿性关节炎的发病率：一项基于人群数据的研究。
The incidence of juvenile rheumatoid arthritis in Quebec: a population data-based study.
机构信息
Université de Montréal, Interdisciplinary Research Centre in Rehabilitation, and Public Health Department of Montreal, Pavillon 7077 du Parc, CP 6128, Succ Centre-ville, Montréal, Qc H3C 3J7, Canada.
出版信息
Pediatr Rheumatol Online J. 2009 Nov 19;7:20. doi: 10.1186/1546-0096-7-20.
OBJECTIVE
To determine the population incidence of juvenile rheumatoid arthritis (JRA) in Quebec.
METHODS
We obtained data from Quebec's physician claims database. Incident cases were defined as having a visit for JRA in 2000, no visit in the previous 3 years, a confirmed diagnosis by an arthritis specialist, or having >/= 2 visits to any physician for JRA, >/= 2 months apart but within 2 years.
RESULTS
Cumulative incidence of JRA was 17.8/100,000. Mean age at diagnosis was 9.8 +/- 4.6 years, 68% were female and more persons were diagnosed in winter. Subjects had a median of 10 medical visits over the first year.
CONCLUSION
Our population based incidence estimate was similar to others. Children and adolescents with JRA are heavy users of medical care. Additional study of environmental or climate- related triggers may be warranted.
目的
确定魁北克幼年特发性关节炎（JRA）的人群发病率。
方法
我们从魁北克的医生索赔数据库中获取数据。新发病例的定义为 2000 年有 JRA 就诊，前 3 年无就诊，经关节炎专家确诊，或有 >/= 2 次因 JRA 就诊于任何医生，相隔 >/= 2 个月但在 2 年内。
结果
JRA 的累积发病率为 17.8/100,000。诊断时的平均年龄为 9.8 +/- 4.6 岁，68%为女性，更多的人在冬季被诊断。患者在第一年中位数有 10 次就诊。
结论
我们的基于人群的发病率估计与其他研究相似。患有 JRA 的儿童和青少年是医疗保健的重度使用者。可能需要进一步研究环境或与气候相关的触发因素。
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