布比卡因在小鼠血清、心脏和脑组织中的动力学：地西泮预处理的影响
Bupivacaine kinetics in serum, cardiac and brain tissues: effect of diazepam pretreatment in mice.
作者信息
Bruguerolle B, Merland V, Prat M
机构信息
Laboratoire de Pharmacologie Médicale, Faculté de Médecine de Marseille.
出版信息
Life Sci. 1991;48(6):569-74. doi: 10.1016/0024-3205(91)90472-n.
PMID:1992291
Abstract
This study was designed to document possible changes in bupivacaine kinetics in serum and in heart and brain tissues induced by a pretreatment with diazepam in mice. When diazepam is associated with bupivacaine, elimination of bupivacaine from serum and cardiac tissues is decreased; statistical differences were not found in brain tissues.
摘要
本研究旨在记录地西泮预处理对小鼠血清、心脏和脑组织中布比卡因动力学可能产生的变化。当布比卡因与地西泮联用时，血清和心脏组织中布比卡因的消除减少；脑组织中未发现统计学差异。
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