Department of Internal Medicine, National Defense Medical College, Saitama, Japan.
Gastrointest Endosc. 2010 Feb;71(2):406-12. doi: 10.1016/j.gie.2009.09.018. Epub 2009 Nov 17.
Intraductal papillary mucinous neoplasm (IPMN) of the pancreas may extend to other organs. However, it is rare for a histopathologically benign IPMN to rupture other organs, particularly multiple organs. There has been no report of a benign IPMN rupturing both the stomach and duodenum.
We experienced a very rare case and make personal remarks based on bibliographical consideration.
Case report.
National Defense Medical College.
A patient with IPMN.
EGD, ERCP, and pancreatoduodenectomy.
We report a case of benign IPMN of the pancreas extending to two adjacent organs. A 77-year-old male who was diagnosed as having IPMN by CT, MRI, upper GIF, and ERCP underwent pancreatoduodenectomy for a mass of 4.2 cm in diameter. Pathological examinations revealed that the IPMN was composed of adenoma. Intraluminal nodular growth was observed in the duodenal gland tissue, and abnormal growth was observed in the fistula to the stomach. According to a literature review based on PubMed data up until March 2009, it is rare for a benign IPMN to penetrate two adjacent organs.
胰腺内导管乳头状黏液性肿瘤（IPMN）可能会延伸至其他器官。然而，组织病理学上良性的 IPMN 很少会穿透其他器官，特别是多个器官。目前尚无良性 IPMN 同时穿透胃和十二指肠的报道。
我们报告了一个非常罕见的病例，并基于文献回顾进行了个人评论。
病例报告。
国防医学院。
一名患有 IPMN 的患者。
EGD、ERCP 和胰十二指肠切除术。
我们报告了一例胰腺良性 IPMN 延伸至两个相邻器官的病例。一名 77 岁男性因 CT、MRI、上消化道内镜和 ERCP 诊断为 IPMN，因直径 4.2cm 的肿块而行胰十二指肠切除术。病理检查显示 IPMN 由腺瘤组成。在十二指肠腺组织中观察到腔内结节性生长，在通向胃的瘘管中观察到异常生长。根据截至 2009 年 3 月基于 PubMed 数据的文献回顾，良性 IPMN 穿透两个相邻器官的情况较为罕见。
