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强迫症患者的自杀意念。

Suicidal ideation in patients with obsessive-compulsive disorder.

机构信息

Department of Psychiatry, Adnan Menderes University, Aydin, Turkey.

出版信息

Psychiatry Res. 2010 Jan 30;175(1-2):104-8. doi: 10.1016/j.psychres.2009.03.012. Epub 2009 Nov 17.

DOI:10.1016/j.psychres.2009.03.012
PMID:19923009
Abstract

The risk factors for suicidal behaviour in obsessive-compulsive disorder (OCD) have been less studied compared than in other anxiety disorders. In the present study, we examined the demographic and clinical correlates of current suicidal ideation (SI) in patients with OCD. Forty-four patients were grouped into those with (n=23) and without current SI (n=21) as assessed by the Scale for Suicidal Ideation. The Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) was used to assess the obsessive-compulsive (OC) symptomatology. Following Bonferroni correction, only the severity of depression differed significantly between the two groups. The presence of major depression and aggressive obsessions, the level of hopelessness, and the severity of OC symptomatology were significant predictors of current SI in patients with OCD. The relatively low frequency of some comorbid Axis I disorders is based on small sample size and therefore may be vulnerable to type II error. We did not examine the relationship between the recent suicidal attempts and OCD. Also, we did not assess the effect of impulsivity in the occurrence of SI in patients with OCD. Associated depression, hopelessness, and aggressive obsessions might play an important role in the occurrence of SI in patients with OCD. However, future studies with a psychological autopsy design are required to systematically determine the presence for OCD among those who have completed suicide.

摘要

与其他焦虑障碍相比,强迫症(OCD)患者自杀行为的风险因素研究较少。在本研究中,我们检查了 OCD 患者当前自杀意念(SI)的人口统计学和临床相关性。44 名患者根据自杀意念量表(Scale for Suicidal Ideation)分为有(n=23)和无当前 SI(n=21)两组。耶鲁-布朗强迫症量表(Yale-Brown Obsessive-Compulsive Scale,Y-BOCS)用于评估强迫症症状。经 Bonferroni 校正后,只有两组之间的抑郁严重程度差异具有统计学意义。重度抑郁症和攻击性强迫观念、无望感水平以及强迫症症状严重程度是 OCD 患者当前 SI 的显著预测因子。一些伴发的轴 I 障碍的相对低频率是基于小样本量,因此可能容易出现 II 型错误。我们没有检查最近自杀尝试与 OCD 之间的关系。此外,我们没有评估冲动性在 OCD 患者 SI 发生中的作用。相关的抑郁、无望感和攻击性强迫观念可能在 OCD 患者 SI 的发生中起重要作用。然而,需要进行具有心理尸检设计的未来研究来系统地确定在自杀者中 OCD 的存在。

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