Norrving B, Cronqvist S
Department of Neurology, University Hospital, Lund, Sweden.
Neurology. 1991 Feb;41(2 ( Pt 1)):244-8. doi: 10.1212/wnl.41.2_part_1.244.
We describe the acute and long-term prognosis in 43 patients with lateral medullary infarction (LMI) collected from a population-based stroke registry from 1982 to July 1988. Mean age was 63.9 years and median time of follow-up was 33 months. In the acute phase, 5 patients (11.6%) died from respiratory and cardiovascular complications and 2 new strokes occurred, both in the posterior circulation. During follow-up, recurrent vertebrobasilar territory strokes occurred in only 2 patients (a rate of 1.9% per year). The mechanisms of stroke were vertebral artery (VA) branch occlusion, causing a medial medullary syndrome, and basilar artery thrombosis propagating from a contralateral, distal VA stenosis. In the acute phase of LMI, respiratory and cardiovascular events, presumably caused by autonomic dysfunction related to the lateral medullary lesion, are the major hazards. Recurrent posterior circulation strokes were uncommon during follow-up.
我们描述了1982年至1988年7月从一个基于人群的卒中登记处收集的43例延髓外侧梗死（LMI）患者的急性期和长期预后。平均年龄为63.9岁，中位随访时间为33个月。急性期，5例患者（11.6%）死于呼吸和心血管并发症，2例发生新的卒中，均在后循环。随访期间，仅2例患者发生椎基底动脉区域复发性卒中（每年发生率为1.9%）。卒中机制为椎动脉（VA）分支闭塞，导致内侧延髓综合征，以及基底动脉血栓形成从对侧远端VA狭窄蔓延而来。在LMI急性期，呼吸和心血管事件，可能由与延髓外侧病变相关的自主神经功能障碍引起，是主要危害。随访期间后循环复发性卒中并不常见。
