Department of Rehabilitation Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, 1111 Xianxia Road, Shanghai, 200336, China.
Department of Anesthesiology, Minhang Hospital, Fudan University, Shanghai, 201100, China.
Neurol Sci. 2022 Jan;43(1):477-484. doi: 10.1007/s10072-021-05247-6. Epub 2021 May 11.
To investigate the effect of transcranial direct current stimulation (tDCS) combined with conventional comprehensive rehabilitation on dysphagia after brainstem stroke.
Forty brainstem stroke patients were randomly divided into tDCS group and conventional comprehensive treatment group, including 20 patients in each group. Both groups were given routine swallowing function training, and tDCS group added transcranial direct current stimulation (tDCS). The Dysphagia Outcome and Severity Scale (DOSS) and Functional Dysphagia Scale (FDS) were evaluated respectively before and after 8 weeks of continuous treatment with VFSS. The white blood cell (WBC), c-reactive protein, prealbumin (PAB), albumin (Alb), and hemoglobin (Hb) were also compared between the two groups before and after 8 weeks of continuous treatment.
After 8 consecutive weeks of treatment, the score of DOSS scale and FDS scale in both groups was improved (P < 0.05), WBC and CRP were decreased (P < 0.05), and Alb and Hb were improved (P < 0.05), and PAB had no differences (P=0.474). The tDCS group was superior to conventional comprehensive group in improving the swallowing function and nutritional indexes (P < 0.05).
tDCS therapy combined with routine training can improve the swallowing function and nutritional status of patients, and reduce infection.
研究经颅直流电刺激（tDCS）联合常规综合康复治疗对脑干卒中后吞咽障碍的影响。
将 40 例脑干卒中患者随机分为 tDCS 组和常规综合治疗组，每组 20 例。两组均给予常规吞咽功能训练，tDCS 组加用经颅直流电刺激（tDCS）。分别在 8 周连续治疗前后采用视频透视吞咽功能检查（VFSS）评估吞咽障碍结局和严重程度量表（DOSS）和功能性吞咽障碍量表（FDS）。比较两组治疗前后 8 周白细胞（WBC）、C 反应蛋白（CRP）、前白蛋白（PAB）、白蛋白（Alb）和血红蛋白（Hb）。
连续治疗 8 周后，两组 DOSS 量表和 FDS 量表评分均有所改善（P<0.05），WBC 和 CRP 降低（P<0.05），Alb 和 Hb 升高（P<0.05），PAB 差异无统计学意义（P=0.474）。tDCS 组在改善吞咽功能和营养指标方面优于常规综合组（P<0.05）。
tDCS 治疗联合常规训练可改善患者吞咽功能和营养状况，降低感染率。
