Kneisl J S, Finn H A, Simon M A
Orthopaedic Surgery, Northwestern University, Chicago, Illinois.
Orthop Clin North Am. 1991 Jan;22(1):105-19.
Limb-salvage surgery involving mobile knee reconstructions for malignant tumors about the distal femur is a desirable and achievable goal. With limb salvage, the survival rate does not decrease significantly, and the resulting function is superior to when an amputation plus a prosthesis are used. Immediate and delayed morbidity is greater after limb-salvage surgery than after amputation. However, with thorough preoperative planning, use of neoadjuvant chemotherapy as indicated, and an experienced team of surgeons, limb-salvage surgery can provide a mobile knee with excellent function in the vast majority of cases for patients with malignant tumors of the distal femur.
对于股骨远端恶性肿瘤,采用可活动膝关节重建的保肢手术是一个理想且可实现的目标。通过保肢手术,生存率不会显著降低,且所获得的功能优于截肢加安装假肢的情况。保肢手术后的近期和远期发病率高于截肢术后。然而,通过全面的术前规划、根据指征使用新辅助化疗以及经验丰富的外科团队,保肢手术在绝大多数情况下能够为股骨远端恶性肿瘤患者提供功能良好的可活动膝关节。